What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Flomax MR (Tamsulosin)
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Product Details
Description
Your doctor may prescribe Flomax MR, which is a modified-release medication designed to alleviate symptoms of benign prostatic hyperplasia (BPH). BPH is a condition in which the prostate gland is enlarged, causing urinary difficulties.
Tamsulosin is an alpha-1 adrenergic blocker class that relaxes the prostate and bladder neck muscles, improving urine flow and reducing symptoms such as difficulty starting urination, weak stream, and frequent or urgent urination.
Fact Table
Formula
C20H28N2O5S
License
US FDA, EMA
Bioavailability
~100%
Legal status
Prescription only (?)
Chemical Name
5-[(2R)-2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide hydrochloride
Elimination half-life
9-13 hours
Dosage (Strength)
0.4 mg modified-release capsules
Pregnancy
Not indicated for use in women
Brands
Flomax, Flomax MR
Protein binding
94-99%
PubChem CID
129211
MedlinePlus
a698012
ChEBI
CHEBI:9396
ATC code
G04CA02
DrugBank
DB00706
KEGG
D08511
Routes of administration
Oral
Directions
The usual dosage is 0.4 mg by mouth once daily. The capsule should not be opened, crushed, or chewed but swallowed whole.
Do not stop or start this drug without speaking with your doctor first.
Ingredients
The active ingredient in Flomax MR is tamsulosin extended-release.
Interactions
Tell your healthcare provider if you are taking any of the following drugs:
- Abiraterone Acetate
- Alfuzosin
- Boceprevir
- Bunazosin
- Carbamazepine
- Ceritinib
- Clarithromycin
- Cobicistat
- Conivaptan
- Dapiprazole
- Desvenlafaxine
- Doxazosin
- Escitalopram
- Fedratinib
- Idelalisib
- Indinavir
- Itraconazole
- Ketoconazole
- Lopinavir
- Mavacamten
- Melphalan
- Moxisylyte
- Nefazodone
- Nelfinavir
- Omaveloxolone
- Paroxetine
- Phenobarbital
- Phenoxybenzamine
- Phentolamine
- Posaconazole
- Prazosin
- Primidone
- Ritonavir
- Saquinavir
- Sertraline
- Silodosin
- Tadalafil
- Telaprevir
- Telithromycin
- Terazosin
- Tolazoline
- Trimazosin
- Urapidil
- Vardenafil
- Venlafaxine
- Voriconazole
Cautions
Flomax MR can cause dizziness and fainting, especially when starting treatment or increasing the dose. Avoid driving or operating heavy machinery until you understand how Flomax MR affects you.
Inform the healthcare provider of any planned cataract or glaucoma surgery, as tamsulosin can affect pupil dilation during these procedures.
Flomax MR should be used with caution in patients with a history of low blood pressure or those susceptible to orthostatic hypotension, a condition where blood pressure drops significantly upon standing.
Side Effects
Common adverse reactions to this drug may include:
- Abnormal ejaculation
- Asthenia
- Backache
- Dizziness
- Headache
- Infectious disease
- Insomnia
- Rhinitis
- Retinal detachment (serious)
- Somnolence
- Priapism (serious)
References
Flomax [package insert]. Norman, OK: Astellas; November 2009.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13902
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