Firdapse (Amifampridine)
What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
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Prescription Required
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Product Details
Description
Firdapse (amifampridine) is a prescription medication used for treating Lambert-Eaton myasthenic syndrome (LEMS) in patients who are at least 6 years of age.
Firdapse is available in 10 mg oral tablets.
Fact Table
Formula
C5H6N2
License
US FDA, EMA
Bioavailability
75-80%
Legal status
Prescription only
Chemical Name
3,4-Diaminopyridine
Elimination half-life
3.5 hours
Dosage (Strength)
10 mg, 20 mg tablets
Pregnancy
Consult a doctor
Brands
Firdapse
Protein binding
N/A
PubChem CID
13440
MedlinePlus
a619031
ChEBI
63929
ATC code
N07XX05
DrugBank
DB05030
KEGG
D09343
Routes of administration
Oral
Directions
Take Firdapse exactly as prescribed by your doctor. Your doctor will tell you how much Firdapse you should take and how often.
Carefully read the information leaflet that comes with your prescription. If you have any questions or concerns, reach out to your doctor or pharmacist.
Storing Firdapse:
Keep Firdapse tablets at room temperature between 68°F and 77°F (20°C and 25°C) and out of reach of children. If you make a Firdapse suspension, keep it in the refrigerator between 36°F and 46°F (2°C and 8°C) for up to 24 hours.
Ingredients
The active ingredient in Firdapse 10 mg is amifampridine. Inactive ingredients include calcium stearate, colloidal silicon dioxide, and microcrystalline cellulose.
Contraindications
Patients who have a history of seizures or are allergic to amifampridine phosphate or another aminopyridine should not take Firdapse.
Cautions
- Before you start taking Firdapse, talk to your doctor about:
- All the prescription and over-the-counter medications you take
- Your allergies
- Your current health problems and past medical history
- Your pregnancy or breastfeeding status
Side Effects
Tingling around the mouth, tongue, face, fingers, toes, and other body parts; upper respiratory infection; stomach pain; nausea; diarrhea; headache; increased liver enzymes; back pain; high blood pressure; and muscle spasms are the most common side effects of Firdapse. However, other side effects may also occur. Immediately inform your doctor of side effects that bother you or won’t go away.
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Reference:
Firdapse. Coral Gables, FL: Catalyst Pharmaceuticals, Inc.; 2022.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 14446
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