What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Ferriprox (Deferiprone)
Prescription Required
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Product Details
Description
Ferriprox is a prescription medication used to treat iron overload from blood transfusions in adult and pediatric patients who are at least 8 years of age and have thalassemia syndromes, sickle cell disease, or other anemias.
Ferriprox comes in functionally scored 500 mg (three times a day) and 1000 mg tablets (twice a day and three times a day) for oral administration.
Directions
Take Ferriprox exactly as prescribed by your doctor. If you have any questions or concerns, talk to your doctor or pharmacist.
Your doctor will determine an appropriate dose for you, as the tablets come in three different formulations and have distinct identifying characteristics.
Store Ferriprox tablets between 20°C to 25°C (68°F to 77°F) and out of reach of children.
Ingredients
Deferiprone is the active ingredient in Ferriprox.
The inactive ingredients in the 500 mg tablets include microcrystalline cellulose, magnesium stearate, colloidal silicon dioxide, hypromellose, polyethylene glycol, titanium dioxide.
The inactive ingredients in the 1000 mg tablets (twice a day) include hypromellose acetate succinate, magnesium oxide, colloidal silicon dioxide and magnesium stearate, triethyl citrate, talc, titanium dioxide, and methacrylic acid and ethyl acrylate copolymer.
The inactive ingredients in the 1000 mg tablets (three times a day) include methylcellulose, crospovidone, and magnesium stearate; Coating - hypromellose, hydroxypropyl cellulose, macrogol, and titanium dioxide.
Contraindications
Patients who are allergic to deferiprone to any of the excipients in the medication should not take Ferriprox.
Cautions
Ferriprox is associated with the following FDA Boxed Warning:
- Agranulocytosis can occur, which can lead to serious infections and death. Neutropenia may occur before agranulocytosis develops.
- The absolute neutrophil count (ANC) should be measured before starting Ferriprox; regular monitoring should occur during therapy.
- Ferriprox should be stopped if neutropenia develops.
- Ferriprox should be stopped if infection develops; the ANC should be more frequently monitored.
- Patients who experience any symptoms of an infection should consult their doctor right away.
- Before you start taking Ferriprox, talk to your doctor about:
- All the prescription and over-the-counter medications you take, including supplements and vitamins
- Your allergies
- Your current health problems and past medical history
- Your pregnancy or breastfeeding status
- Liver enzymes may increase during Ferriprox treatment; therefore, they should be monitored monthly.
- A deficiency in zinc may occur during Ferriprox treatment; supplements may be needed.
- Ferriprox can cause harm to an unborn baby. Effective birth control methods should be used during treatment and for at least 6 months after receiving the last dose.
Side Effects
Nausea, vomiting, abdominal pain, joint pain, increased liver enzymes, abnormal white blood cell counts, fever, bone pain, headache, pain in the arms and legs, sickle cell anemia with crisis, back pain, mouth and throat pain, common cold, and cough are common Ferriprox side effects. However, these are not all the side effects that can occur. Contact your doctor right away if you have side effects that bother you or won’t go away.
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Reference
Ferriprox. Cary, NC: Chiesi USA, Inc.; 2021.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13843
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