What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Eysuvis (Loteprednol Etabonate Ophthalmic Suspension)

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Brand

Eysuvis (Loteprednol Etabonate Ophthalmic Suspension)

Prescription Required

Strength
Qty
0.25% 8.3ml

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  • Product Details

    Description

    Eysuvis (loteprednol etabonate ophthalmic suspension) 0.25% is an eye drop that is used for up to two weeks to treat signs and symptoms of dry eye disease.


    Fact Table

    Formula

    C24H31ClO7

    License

    US FDA

    Bioavailability

    None

    Legal status

    Rx-Only

    Chemical Name

    Loteprednol etabonate

    Elimination half-life

    2.8 hrs

    Dosage (Strength)

    0.25% 8.3ml

    Pregnancy

    Consult Doctor

    Brands

    Eysuvis

    Protein binding

    95%

    PubChem CID

    444025

    MedlinePlus

    a619025

    ChEBI

    31784

    ATC code

    S01BA14

    DrugBank

    DB14596

    KEGG

    D01689

    Routes of administration

    Eye drops

    Directions

    Eysuvis is an eye drop suspension that contains 2.5 mg/mL of loteprednol etabonate.

    Follow the instructions that come with your Eysuvis prescription. Talk to your doctor or pharmacist about any questions or concerns you have about your prescription.

    Before using Eysuvis, wash your hands thoroughly. To prevent contamination, keep the dropper tip from touching surfaces. Shake the bottle for 2 to 3 seconds. Place one to two drops into each eye four times a day.

    Wait at least 5 minutes between using Eysuvis and other eye drops. 

    Remove contact lenses before using Eysuvis. You may reinsert them 15 minutes after using Eysuvis. 

    Ingredients

    The active ingredient in Eysuvis is loteprednol etabonate, a corticosteroid.

    Contraindications

    Do not use Eysuvis if you have a viral eye disease such as epithelial herpes simplex keratitis, vaccinia, and varicella.

    Do not use Eysuvis if you have a mycobacterial eye infection or fungal eye disease.

    Cautions

    • Before you start treatment with Eysuvis, inform your doctor:
      • Of all the medications you take. These include prescription, nonprescription, vitamins, and herbal supplements.
      • Of your allergies.
      • Of your health conditions. 
      • If you are pregnant or plan to become pregnant.
      • If you are breastfeeding or plan to breastfeed.
    • Eysuvis may cause prolonged healing and perforation of the cornea.
    • Using Eysuvis for a long period of time may cause vision problems such as glaucoma.
    • Eysuvis may cause cataracts.
    • Eysuvis may increase the risk of secondary eye infections and mask or worsen an existing infection.
    • Eysuvis can lengthen the course of or worsen viral eye infections such as herpes simplex. Caution should be used if you have ever had herpes simplex.
    • Using Eysuvis for a long period of time can increase the risk of fungal corneal infections. 

    Side Effects

    Eysuvis can cause side effects such as pain in the instillation site. However, this is not the only possible side effect of Eysuvis. Contact your doctor right away if you have side effects that become troublesome or persistent.

    Reference:

    Eyesuvis (loteprednol etabonate ophthalmic suspension) 0.25%, for topical ophthalmic use. Watertown, MA: Kala Pharmaceuticals, Inc.; 2020.



    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13654

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