Entyvio (Vedolizumab)
What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
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Prescription Required
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Product Details
Description
Entyvio (vedolizumab) is an injectable medication administered to treat adults with moderate-to-severe ulcerative colitis or Crohn’s disease.
Entyvio for subcutaneous (underneath the skin) injection is available in single-dose prefilled syringes and pens containing 108 mg/0.68 mL solution.
Fact Table
Formula
C6528H10018N1734O2066S40
License
US FDA, EMA
Bioavailability
Not applicable (IV administration)
Legal status
Prescription only (Rx)
Chemical Name
Vedolizumab
Elimination half-life
~25 days
Dosage (Strength)
300 mg/vial
Pregnancy
Consult a doctor
Brands
Entyvio
Protein binding
~98%
PubChem CID
24964643
MedlinePlus
a614014
ChEBI
CHEBI:134721
ATC code
L04AA33
DrugBank
DB09033
KEGG
D09993
Routes of administration
Intravenous (IV)
Directions
Use Entyvio exactly as prescribed by your doctor. Your doctor will determine an appropriate treatment regimen for you, including Entyvio dosing. A healthcare professional will teach you or a caregiver how to properly store, prepare, administer, and discard Entyvio.
Entyvio should be injected in the abdomen, thighs, or upper arms. Injection sites should be rotated with each injection.
Carefully read the medication guide that comes with your prescription for product use information. Tell your doctor or pharmacist about any questions or concerns you may have about the medication.
Needles and syringes should never be reused or shared with others.
Ingredients
The active ingredient in Entyvio is vedolizumab.
Inactive ingredients include arginine hydrochloride, citric acid monohydrate, histidine, histidine monohydrochloride, polysorbate 80, sodium citrate dihydrate, and Sterile Water for Injection.
Contraindications
Patients with an allergy to Entyvio or to any of the other ingredients should not receive it.
Cautions
- Entyvio is associated with the following warnings and precautions:
- Hypersensitivity reactions
- Infections
- Progressive multifocal leukoencephalopathy
Side Effects
Nasopharyngitis, headache, joint pain, nausea, fever, upper respiratory tract infection, fatigue, cough, bronchitis, influenza, back pain, rash, itching, sinusitis, oropharyngeal pain, and pain in the legs or arms are common Entyvio side effects; however, other side effects may also occur. Immediately inform your doctor of any side effects that bother you or won’t go away.
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Reference
Entyvio. Lexington, MA: Takeda Pharmaceuticals U.S.A., Inc.; 2023.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 14685
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