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Elmiron (Pentosan Polysulfate Sodium)

Brand

Elmiron (Pentosan Polysulfate Sodium)

Prescription Required

Strength
Qty
100mg
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Generic Equivalent - Elmiron (Pentosan Polysulfate Sodium)

Prescription Required

Strength
Qty
100mg
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  • Related Products & Conditions

  • Product Details

    Description

    Elmiron is used to relieve bladder pain or discomfort caused by interstitial cystitis, also known as painful bladder syndrome.

    Elmiron is available in a 100 mg oral capsule. The Elmiron generic is pentosan polysulfate sodium.

    Directions

    Take Elmiron as your doctor has prescribed. If you have any questions or concerns, talk to your doctor or pharmacist.

    The recommended Elmiron dose is 100 mg by mouth three times a day. Take the capsules with water at least 1 hour before or two hours after meals. Your doctor will tell you how long you should take Elmiron.


    Fact Table

    Formula

    (C5H6Na2O10S2)n

    License

    US FDA

    Bioavailability

    -

    Legal status

    Rx-Only

    Chemical Name

    Pentosan polysulfate

    Elimination half-life

    4.8 hours

    Dosage (Strength)

    100mg

    Pregnancy

    Not recommended

    Brands

    Elmiron

    Protein binding

    -

    PubChem CID

    37720

    MedlinePlus

    a602007

    ChEBI

    -

    ATC code

    C05BA04

    DrugBank

    DB00686

    KEGG

    D05428

    Routes of administration

    Oral

    Ingredients

    Pentosan polysulfate sodium is the active ingredient contained in each Elmiron capsule. Inactive ingredients include microcrystalline cellulose, magnesium stearate, gelatin, pharmaceutical glaze (modified) in SD-45, synthetic black iron oxide, FD and C Blue No. 2 aluminum lake, FD and C Red No. 40 aluminum lake, FD and C Blue No. 1 aluminum lake, D and C Yellow No. 10 aluminum lake, n-butyl alcohol, propylene glycol, SDA-3A alcohol, and titanium dioxide.

    Contraindications

    Do not take Elmiron if you are allergic to the drug or to any of its components.

    Cautions

    • Before you begin treatment with Elmiron, you should tell your doctor about:
      • All the medications you take
      • Your allergies
      • Your health history and current health problems
      • Your pregnancy or breastfeeding status
    • Elmiron may cause pigment changes in the retina and vision problems.
    • Elmiron may cause bleeding. You should watch for signs and symptoms of bleeding such as bleeding from your gums; dark, tarry stools; and nosebleeds that won't stop after 10-15 minutes of applied pressure. Seek medical care right away if any of these effects occur. You should also seek medical care right away if you have fallen and hit your head.
    • Elmiron may cause hair loss.
    • Caution should be used if you have liver problems.

    Side Effects

    Elmiron side effects include stomach pain, diarrhea, and dehydration; however, these are not all the side effects that can occur. Contact your doctor right away if you have side effects that bother you or won't go away.

    Reference:

    Elmiron - 100 mg. Titusville, NJ: Janssen Pharmaceuticals, Inc.; 2021.


    Frequently Asked Questions about Elmiron (Pentosan Polysulfate Sodium)


    What is Elmiron used for?

    Elmiron (pentosan polysulfate sodium) is primarily used to treat interstitial cystitis, a chronic bladder condition causing bladder pain and urinary urgency.


    Why is Elmiron so expensive?

    Elmiron's high cost can be attributed to several factors, including limited competition in the market, development costs, and the complexity of manufacturing the drug.


    Is Elmiron a high-risk medication?

    Elmiron is generally considered safe when used as prescribed, but like any medication, it carries potential risks. Some studies have linked long-term use of Elmiron with potential retinal damage, though further research is ongoing.


    How long can you take Elmiron for?

    The duration of Elmiron treatment depends on individual circumstances and the severity of the condition. It's typically used as a long-term therapy, and patients should follow their doctor's guidance regarding duration.


    What is the success rate of Elmiron?

    Elmiron's effectiveness varies among individuals. Some patients experience significant relief from symptoms, while others may not respond as well. Success rates can be influenced by factors such as the severity of the condition and individual response to treatment.


    Can you buy Elmiron over the counter?

    No, Elmiron is not available over the counter. It requires a prescription from a healthcare provider.


    What are the side effects of Elmiron?

    Common side effects of Elmiron may include hair loss, diarrhea, nausea, headache, and rash. Rare but serious side effects may include vision changes and allergic reactions. Patients should consult their healthcare provider if they experience any concerning side effects.


    How does Elmiron work?

    The exact mechanism of action of Elmiron in treating interstitial cystitis is not fully understood. It is believed to coat the bladder's lining, providing a protective barrier and helping to alleviate symptoms of pain and urgency.


    Is Elmiron FDA approved?

    Yes, Elmiron is FDA approved for the treatment of interstitial cystitis.


    How long does Elmiron stay in your system?

    Elmiron has a half-life of about 3 to 4 hours, meaning it typically stays in the system for about 24 hours after the last dose.


    How long does Elmiron take to work?

    Elmiron's therapeutic effects may not be immediately noticeable. It may take several weeks or even months of consistent use before patients experience significant improvement in symptoms. Patience and adherence to the prescribed regimen are important.



    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 1503

  • Product Reviews

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    “The price was right and I received delivery in approximately two weeks. I will be taking them soon and will be able to tell if they work as well as the ones previously bought in the USA.”
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    June 14, 2022 by patty K. (Ohio, United States)
    “only been on a couple of weeks not enough time to determine if is effective or not.”

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