What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Eliquis (Apixaban)
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Product Details
Description
ELIQUIS (Apixaban) is a medication that may be prescribed for one of the following reasons:
- Treat deep vein thrombosis (DVT) or pulmonary embolism (PE) and to reduce the risk of it happening again
- Provide prophylaxis for DVT and PE in certain high-risk patients, like those undergoing knee or hip replacement surgery
- Reduce the risk of stroke in patients with nonvalvular atrial fibrillation
If a clot forms in the veins, it can break off and lead to harmful and sometimes deadly events like a cardiovascular accident (stroke), myocardial infarction (heart attack), or PE (clot in the lungs). Certain people are at high risk of clot formation, including those who have had a clot before and those with atrial fibrillation.
Atrial fibrillation is an irregular heart rhythm where one of the chambers of the heart "quivers" instead of efficiently pumping blood. This causes blood to stay in one spot and increases the risk of a clot.
ELIQUIS works by targeting a protein in the clotting cascade, called factor Xa (Ten A). Shutting off this protein slows down clot formation, preventing their formation.
Fact Table
Formula
C25H25N5O4
License
EU EMA, US FDA
Bioavailability
50%
Legal status
RX Only
Chemical Name
Apixaban
Elimination half-life
9-14 hours
Dosage (Strength)
2.5mg, 5mg (Brand and Generic)
Pregnancy
Apixaban should not be taken during pregnancy.
Brands
Eliquis
Protein binding
87%
PubChem CID
10182969
MedlinePlus
a613032
ChEBI
72296
ATC code
B01AF02
DrugBank
DB06605
KEGG
D03213
Routes of administration
By Mouth
Directions
The normal dose of ELIQUIS (apixaban) is 5 mg twice daily.
The dose may be decreased to 2.5 mg twice in certain patients based on characteristics like weight, age, and kidney function.
Ingredients
The active ingredient of ELIQUIS is apixaban.
Cautions
ELIQUIS cannot be used by those with artificial heart valves.
Patients with triple phospholipid syndrome (a genetic clotting disorder) should not use ELIQUIS.
If you experience bleeding or bruising that does not stop while taking ELIQUIS, call your doctor.
Side Effects
Since ELIQUIS works by slowing the clotting cascade, the main side effects are related to bleeding. Examples of major bleeding events include:
- Blood in the urine or stool
- Gastrointestinal bleeding
- Hemorrhagic stroke
- Intracranial hemorrhage
Example of minor side effects related to bleeding include:
- Bleeding gums
- Bruising
- Cuts that take longer to heal
- Nose bleeds
Speak with your doctor for management strategies around bleeding side effects and for a full list.
To get the best price of Eliquis Medication, buy ELIQUIS online form a trusted retailer. ELIQUIS cost at Canada Pharmacy is competitive.
References
- Eliquis [package insert].New York, NY: Bristol-Myers Squibb, 2010
Frequently Asked Questions about Eliquis (Apixaban)
What is Eliquis apixaban used for?
Apixaban, also known as Eliquis, helps prevent strokes or blood clots in people with atrial fibrillation. Atrial fibrillation is a condition where the heart beats irregularly, increasing the risk of clot formation. This use of apixaban is specifically for cases not caused by heart valve disease.
What is the most common side effect of Eliquis?
The most common side effect of Eliquis (apixaban) is unwanted bleeding. While taking Eliquis, watch out for minor bleeding like nosebleeds or light bruising. However, if you experience persistent bleeding or notice blood in your urine or stool, these could indicate a serious bleed and require immediate attention.
What should you avoid while taking Eliquis?
Eliquis (apixaban) can be taken with or without most foods. It’s advisable to avoid consuming grapefruit and grapefruit products since they can interact with Eliquis and potentially increase its blood levels, which may lead to a higher risk of bleeding. However, if you regularly consume grapefruit, consult your doctor. They may consider adjusting your Eliquis dosage accordingly.
Is Eliquis a high risk medication?
Eliquis is a high-alert medicine. While it works well, not following instructions exactly can lead to serious problems, like bleeding or stroke. Always listen to your doctor carefully.
Can you eat eggs while taking Eliquis?
When it comes to Eliquis (apixaban), there are no specific foods you need to avoid. Unlike some other blood thinners, Eliquis doesn’t interact with vitamin K-rich foods like spinach, broccoli, or kale.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13142
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