Description
Edurant (rilpivirine) is a prescription medication that is used with other medications to treat human immunodeficiency virus type 1 (HIV-1) infection in patients who are at least 12 years of age and weigh at least 35 kg (77 lbs).
Edurant is available in 25 mg tablets for oral administration.
Fact Table |
Formula |
C22H18N6 |
License |
US FDA, US DailyMed |
Bioavailability |
43% |
Legal status |
Rx-Only |
Chemical Name |
Rilpivirine |
Elimination half-life |
45 hours |
Dosage (Strength) |
25mg |
Pregnancy |
Consult Doctor |
Brands |
Edurant |
Protein binding |
99.7% |
PubChem CID |
6451164 |
MedlinePlus |
a611037 |
ChEBI |
68606 |
ATC code |
J05AG05 |
DrugBank |
DB08864 |
KEGG |
D09720 |
Routes of administration |
By mouth |
Directions
Edurant should be taken exactly as prescribed by your doctor. Any questions or concerns can be referred to your doctor or pharmacist.
Recommended dosing with Edurant 25 mg tablet:
One tablet by mouth once daily with a meal.
When also taking rifabutin, the recommended Edurant dose is to take 2 tablets by mouth once daily with a meal.
Ingredients
Rilpivirine hydrochloride is the active ingredient in Edurant. Inactive ingredients include croscarmellose sodium, lactose monohydrate, magnesium stearate, polysorbate 20, povidone K30, and silicified microcrystalline cellulose. The coating of the tablet contains hypromellose 2910 6 mPa.s, lactose monohydrate, PEG 3000, titanium dioxide, and triacetin.
Contraindications
Edurant should not be taken with medications that can decrease its levels in the body, as this can decrease its effectiveness.
Cautions
- Before you start treatment with Edurant, discuss the following with your doctor:
- All the prescription and over-the-counter medications you take
- Your allergies
- Your health conditions and past medical history
- Your pregnancy and breastfeeding status
- Edurant can cause severe skin and hypersensitivity reactions. Seek medical care right away if you develop a rash or any other sign or symptom of a reaction.
- Edurant can cause liver problems, especially in patients with underlying liver disease.
- Edurant can cause depressive disorders.
- Edurant can cause immune reconstitution syndrome and autoimmune disorders.
Side Effects
The most common Edurant medication side effects include depressive disorders, headache, trouble sleeping, and rash. Other side effects may also occur. Tell your doctor right away if you have bothersome or persistent side effects.
You can buy Edurant online at a competitive price and with a valid prescription from your doctor at Canada Pharmacy.
Reference:
- Edurant. Titusville, NJ: Janssen Therapeutics, Division of Janssen Products, LP; 2022.
About Dr. Savannah Muncy (Page Author)
Dr. Muncy (PharmD) studied science and education as an undergraduate before attending the Appalachian College of Pharmacy where she completed her PharmD in three years. She is currently using her pharmacy and healthcare expertise to write medical content for clients all around the world. She is focused on delivering the most current, accurate, and engaging information to healthcare professionals and patients. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 12500