What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Durezol (difluprednate) Ophthalmic Emulsion
Generic Equivalent - Durezol (difluprednate) Ophthalmic Emulsion
Prescription Required
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Product Details
Description
Durezol is a prescription eye medication that your doctor may prescribe for inflammation and pain after or surgery or for the treatment of endogenous anterior uveitis.
After eye surgery, the eye may become painful and inflamed during the healing process. Durezol helps to minimize these symptoms.
Anterior uveitis is the inflammation of the eye's middle layer, including the iris and ciliary body.
Durezol is a topical corticosteroid that works by reducing inflammation and pain in the eyes.
Fact Table
Formula
C27H34F2O7
License
US FDA
Bioavailability
-
Legal status
Rx-only
Chemical Name
Difluprednate
Elimination half-life
-
Dosage (Strength)
0.05%
Pregnancy
No Known Risk
Brands
Durezol
Protein binding
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PubChem CID
32037
MedlinePlus
a609025
ChEBI
31485
ATC code
D07AC19
DrugBank
DB06781
KEGG
D01266
Routes of administration
Eye drops
Directions
After surgery, the standard dose is one drop into the affected eye four times daily for two weeks and twice daily for weeks 3-4.
For endogenous anterior uveitis, the standard dosage is one drop four times daily for 14 days.
Ingredients
The active ingredient in Durezol is difluprednate.
Interactions
Tell your healthcare team about all medications you are taking before starting Durezol. It has the potential to interact with the following eye medications:
- Acular
- Acular LS
- Acuvail
- Bromfenac ophthalmic
- BromSite
- Diclofenac ophthalmic
- Flurbiprofen ophthalmic
- Ilevro
- Ketorolac ophthalmic
- Ketorolac/phenylephrine ophthalmic
- Nepafenac ophthalmic
- Nevanac
- Omidria
- Prolensa
- Voltaren Ophthalmic
Cautions
If you are using this medication after surgery, it is not recommended to use the same bottle for both eyes.
Do not let the dropper tip touch the surface of the eye to avoid contamination with bacteria or other microorganisms.
Do not use Durezol while wearing contact lenses. Wait 15 minutes after applying the medication before placing contacts.
Side Effects
The most common Durezol eye drop side effects can include:
- Anterior chamber inflammation
- Blepharitis
- Blurred vision
- Cataract
- Conjunctival edema
- Corneal edema
- Crusting of the eyelid
- Decreased visual acuity
- Dry eye syndrome
- Eye irritation
- Eye pain
- Eye pruritus
- Headache
- Increased intraocular pressure
- Increased lacrimation
- Ocular hyperemia
- Photophobia
- Uveitis
References
Durezol [package insert]. East Hanover, NJ: Novartis; 2020.
Frequently Asked Questions about Durezol (difluprednate) Ophthalmic Emulsion
What is Durezol (difluprednate) Ophthalmic Emulsion?
Durezol is a prescription eye medication that comes in the form of an ophthalmic emulsion. It contains the active ingredient difluprednate and is used to treat eye inflammation and pain following eye surgery.
How does Durezol work?
Durezol works by reducing inflammation in the eye. The active ingredient, difluprednate, is a corticosteroid that helps to decrease swelling, redness, and pain in the eye.
What conditions is Durezol Ophthalmic Emulsion used to treat?
Durezol is typically prescribed to treat eye conditions that involve inflammation, such as post-operative inflammation following eye surgery, uveitis, and other inflammatory eye disorders.
Is Durezol available over the counter (OTC)?
No, Durezol is not available over the counter. It is a prescription medication, which means you need a doctor's prescription to obtain it.
How should I use Durezol Ophthalmic Emulsion?
Durezol is applied as eye drops. Follow your doctor's instructions carefully. Typically, you will apply one or two drops into the affected eye(s) as directed by your healthcare provider.
Are there any potential side effects of using Durezol?
Like all medications, Durezol may have side effects. Common side effects can include eye irritation, stinging or burning, increased eye pressure, and blurred vision. Be sure to discuss any side effects with your doctor.
Can I use Durezol if I have allergies or other eye conditions?
Inform your healthcare provider about any allergies or other eye conditions you have before starting Durezol. Your doctor will consider your medical history to determine if Durezol is safe and appropriate for you.
How long should I use Durezol Ophthalmic Emulsion?
The duration of Durezol use will be determined by your healthcare provider and the specific condition being treated. Follow your doctor's recommendations regarding the duration of treatment.
Can I wear contact lenses while using Durezol?
It is important to consult your eye doctor regarding the use of contact lenses while using Durezol. In some cases, contact lenses may need to be temporarily avoided during treatment.
Is it safe to use Durezol during pregnancy or while breastfeeding?
If you are pregnant, planning to become pregnant, or breastfeeding, discuss the use of Durezol with your healthcare provider. They can assess the potential risks and benefits and provide guidance on the best course of action.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 11587
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