What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
DuoCort (Hydrocortisone)
Prescription Required
We don't have this generic product yet!
Sign up to get exclusive coupon discounts and be the first to be notified when we have this product available.
-
Product Details
Description
Your doctor may prescribe DuoCort to treat adrenal insufficiency, a condition in which the adrenal glands do not produce enough steroid hormones, particularly cortisol. This deficiency can lead to symptoms like fatigue, muscle weakness, weight loss, and low blood pressure.
The active component in DuoCort, hydrocortisone, is a corticosteroid that mimics cortisol's effects. It helps regulate vital body functions and maintain metabolic balance.
Fact Table
Formula
C21H30O5
License
EMA
Bioavailability
96% (oral)
Legal status
Prescription only (?)
Chemical Name
11ß,17a,21-Trihydroxypregn-4-ene-3,20-dione
Elimination half-life
8-12 hours
Dosage (Strength)
5 mg, 10 mg, 20 mg oral tablets; 5 mg/mL injectable solution
Pregnancy
Consult a doctor
Brands
Duocort, Cortef, Solu-Cortef
Protein binding
70%
PubChem CID
5754
MedlinePlus
a682206
ChEBI
CHEBI:17650
ATC code
H02AB09
DrugBank
DB00741
KEGG
D00085
Routes of administration
Oral, Intravenous, Intramuscular, Rectal
Directions
DuoCort directions are individualized for each person.
Generally, the medication is taken orally once or twice daily.
It is essential to follow your doctor's instructions and not stop the medication suddenly, as this can trigger an adrenal crisis, which is potentially life-threatening.
Ingredients
The active ingredient in DuoCort is hydrocortisone.
Interactions
Common drug-drug interactions may include:
- Abametapir
- Aceclofenac
- Acemetacin
- Aldesleukin
- Amtolmetin Guacil
- Aspirin
- Atazanavir
- Balofloxacin
- Bemiparin
- Besifloxacin
- Bromfenac
- Bufexamac
- Bupropion
- Carbamazepine
- Celecoxib
- Choline Salicylate
- Ciprofloxacin
- Clarithromycin
- Clonixin
- Cobicistat
- Conivaptan
- Cosyntropin
- Darunavir
- Desmopressin
- Dexibuprofen
- Dexketoprofen
- Diclofenac
- Diflunisal
- Dipyrone
- Droxicam
- Enoxacin
- Etodolac
- Etofenamate
- Etoricoxib
- Fedratinib
- Felbinac
- Fenoprofen
- Fepradinol
- Feprazone
- Fexinidazole
- Fleroxacin
- Floctafenine
- Flufenamic Acid
- Flumequine
- Flurbiprofen
- Fosnetupitant
- Gatifloxacin
- Gemifloxacin
- Ibuprofen
- Indomethacin
- Itraconazole
- Ketoprofen
- Ketorolac
- Lenacapavir
- Levofloxacin
- Lomefloxacin
- Lornoxicam
- Loxoprofen
- Lumiracoxib
- Lutetium Lu 177 Dotatate
- Macimorelin
- Mavacamten
- Meclofenamate
- Mefenamic Acid
- Meloxicam
- Morniflumate
- Moxifloxacin
- Nabumetone
- Nadifloxacin
- Nadroparin
- Naproxen
- Nepafenac
- Netupitant
- Niflumic Acid
- Nimesulide
- Nimesulide Beta Cyclodextrin
- Norfloxacin
- Ofloxacin
- Omaveloxolone
- Oxaprozin
- Oxyphenbutazone
- Parecoxib
- Pazufloxacin
- Pefloxacin
- Phenobarbital
- Phenylbutazone
- Piketoprofen
- Piroxicam
- Pranoprofen
- Primidone
- Proglumetacin
- Propyphenazone
- Proquazone
- Prulifloxacin
- Rofecoxib
- Rufloxacin
- Salicylic Acid
- Salsalate
- Sargramostim
- Sodium Salicylate
- Somatrogon-ghla
- Sparfloxacin
- Sulindac
- Tenoxicam
- Tiaprofenic Acid
- Tolfenamic Acid
- Tolmetin
- Tosufloxacin
- Upadacitinib
- Valdecoxib
Cautions
Tell your doctor if you have a history of infections, high blood pressure, diabetes, osteoporosis, or gastrointestinal problems.
Long-term corticosteroid use can result in side effects like a weakened immune system, elevated blood sugar levels, and reduced bone density.
Side Effects
Common adverse reactions may include:
- Altered behavior
- Body fluid retention
- Cataract
- Crisis
- Cushing's syndrome
- Delirium
- Depressed mood
- Disturbance in mood
- Euphoria
- Glaucoma
- Growth retardation
- Hyperglycemia
- Impaired glucose tolerance
- Increased appetite
- Increased blood pressure
- Mania
- Osteoporosis
- Pheochromocytoma
- Psychotic disorder
- Pulmonary tuberculosis
- Weight gain
- With hallucinations
- At increased risk for infection
References
Cortef (hydrocortisone oral) [package insert]. New York, NY: Pfizer; November 2019.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13837
-
Product Reviews
