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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Duaklir Pressair(Aclidinium Bromide / Formoterol Fumarate Dihydrate)

Also Known as Brimica Genuair

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Brand

Duaklir Pressair(Aclidinium Bromide / Formoterol Fumarate Dihydrate)

Prescription Required

Strength
Qty
340mcg / 12mcg (60 doses / inhaler)

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  • Product Details

    Description

    Duaklir Pressair is a prescription inhaler that can be used to treat chronic obstructive pulmonary disease (COPD). COPD is a group of diseases that includes emphysema and chronic bronchitis.

    For people with COPD, the airways of their lungs become hardened and inflamed. It becomes more difficult to breathe because oxygen does not pass as easily into the lungs.

    Duaklir Pressair contains two different medications that help relax the airways of the lungs and make it easier to breathe.

    Fact Table

    Formula

    Aclidinium Bromide: C26H30BrNO4S2 Formoterol Fumarate Dihydrate: C19H24N2O4

    License

    US DailyMed

    Bioavailability

    5%

    Legal status

    Rx-Only

    Chemical Name

    Aclidinium Bromide / Formoterol Fumarate Dihydrate

    Elimination half-life

    Aclidinium Bromide: Approximately 2-3 hours Formoterol Fumarate Dihydrate: 10 hours

    Dosage (Strength)

    340mcg / 12mcg (60 doses / inhaler)

    Pregnancy

    Consult Doctor

    Brands

    Duaklir Pressair

    Protein binding

    Aclidinium Bromide: Approximately 87% Formoterol Fumarate Dihydrate: 61-64%

    PubChem CID

    Aclidinium Bromide: 11625033 Formoterol Fumarate Dihydrate: 11523773

    MedlinePlus

    Not listed

    ChEBI

    Aclidinium Bromide: 65344 Formoterol Fumarate Dihydrate: 408174

    ATC code

    R03AL03

    DrugBank

    Aclidinium Bromide: DB08897 Formoterol Fumarate Dihydrate: DB00983

    KEGG

    Aclidinium Bromide: D08837 Formoterol Fumarate Dihydrate: D07990

    Routes of administration

    Inhalation

    Directions

    Inhale one inhalation of Duaklir Pressair twice daily as directed by your healthcare provider.

    Duaklir Pressair is not a rescue inhaler. It must be used every day for the full effect.

    Ingredients

    Duaklir Pressair contains two different active ingredients: aclidinium 400 mcg and formoterol 12 mcg.

    Interactions

    Duaklir Pressair may interact with the following medications:

    • Anticholinergic Agents
    • Advair Diskus
    • AirDuo Respiclick
    • Anoro Ellipta
    • Bevespi Aerosphere
    • Breo Ellipta
    • Carvedilol
    • Cocaine 
    • Dulera
    • Eluxadoline
    • Foradil Aerolizer
    • Glycopyrrolate
    • Inderal
    • Ipratropium 
    • Labetalol
    • Levosulpiride
    • Linezolid
    • Loxapine
    • Methacholine
    • Nadolol
    • Penbutolol
    • Pindolol
    • Potassium Chloride
    • Potassium Citrate
    • Propranolol
    • Secretin
    • Serevent Diskus
    • Sotalol
    • Stiolto Respimat
    • Striverdi Respimat
    • Symbicort 
    • Tiotropium
    • Trelegy Ellipta
    • Umeclidinium

    Cautions

    Duaklir Pressair is not indicated for the treatment of asthma. It also should not be used for acute bronchospasm. It is a maintenance inhaler and must be taken each day for full effect.

    Tell your doctor if you have a history of heart disease, seizure disorders, thyroid disorders, or diabetes mellitus.

    This medication can worsen narrow-angle glaucoma.

    Side Effects

    Duaklir Pressair side effects may include:

    • Arthralgia
    • Back pain
    • Bronchospasm
    • Cough
    • Dizziness
    • Headache
    • Increased kidney enzymes
    • Influenza
    • Insomnia
    • Limb pain
    • Muscle spasm
    • Musculoskeletal pain
    • Oropharyngeal pain
    • Pruritus
    • Sinusitis
    • Skin rash
    • Tooth Abscess
    • Upper respiratory tract infection
    • Urinary tract infection
    • Urticaria
    • Xerostomia

    References

    1. Duklaior Pressair [package insert]. Morrisville, NC: AstraZeneca; 2019.

    Frequently Asked Questions about Duaklir Pressair


    What is Duaklir Pressair?

    Duaklir Pressair is a prescription medication that combines two active ingredients, Aclidinium Bromide and Formoterol Fumarate Dihydrate. It is used to manage chronic obstructive pulmonary disease (COPD) in adults.


    How does Duaklir Pressair work?

    Duaklir Pressair contains two bronchodilators, Aclidinium Bromide and Formoterol Fumarate Dihydrate. Aclidinium Bromide helps to relax the airways, making it easier to breathe, while Formoterol Fumarate Dihydrate helps to open the air passages, providing relief from COPD symptoms.


    What is Duaklir Pressair used for?

    Duaklir Pressair is primarily used to manage the symptoms of COPD, which may include shortness of breath, wheezing, coughing, and chest tightness. It is not a rescue inhaler and should not be used to treat sudden breathing problems.


    Is Duaklir Pressair a rescue medication for COPD exacerbations?

    No, Duaklir Pressair is not intended as a rescue medication for sudden COPD exacerbations. It is a maintenance medication designed to help control and prevent symptoms of COPD over the long term. If you experience sudden worsening of COPD symptoms, you should use your prescribed rescue inhaler as directed by your healthcare provider.


    How should I use Duaklir Pressair?

    Duaklir Pressair comes in inhalation powder form and is typically taken twice daily, as prescribed by your healthcare provider. It should be inhaled orally, and you should follow the instructions provided with the medication carefully.


    Are there any potential side effects of Duaklir Pressair?

    Like all medications, Duaklir Pressair may cause side effects. Common side effects may include headache, cough, dry mouth, and throat irritation. It's essential to discuss any side effects with your healthcare provider.


    Can I use Duaklir Pressair if I have allergies or other medical conditions?

    You should inform your healthcare provider about any allergies or medical conditions you have before starting Duaklir Pressair. Your healthcare provider will consider your medical history to determine if Duaklir Pressair is safe and appropriate for you.


    Can Duaklir Pressair be used during pregnancy or while breastfeeding?

    It is crucial to discuss the use of Duaklir Pressair with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. They can assess the potential risks and benefits and provide guidance on the best course of action.


    Can I continue using my other COPD medications alongside Duaklir Pressair?

    You should consult your healthcare provider before combining Duaklir Pressair with other COPD medications or inhalers. They can help you create a comprehensive treatment plan that meets your specific needs.


    How long should I use Duaklir Pressair?

    The duration of Duaklir Pressair use will be determined by your healthcare provider. It is generally used as a long-term maintenance medication to manage COPD symptoms effectively.




    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13221

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