Description
Duaklir Pressair is a prescription inhaler that can be used to treat chronic obstructive pulmonary disease (COPD). COPD is a group of diseases that includes emphysema and chronic bronchitis.
For people with COPD, the airways of their lungs become hardened and inflamed. It becomes more difficult to breathe because oxygen does not pass as easily into the lungs.
Duaklir Pressair contains two different medications that help relax the airways of the lungs and make it easier to breathe.
Fact Table
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Formula
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Aclidinium Bromide: C26H30BrNO4S2 Formoterol Fumarate Dihydrate: C19H24N2O4
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License
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US DailyMed
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Bioavailability
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5%
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Legal status
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Rx-Only
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Chemical Name
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Aclidinium Bromide / Formoterol Fumarate Dihydrate
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Elimination half-life
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Aclidinium Bromide: Approximately 2-3 hours Formoterol Fumarate Dihydrate: 10 hours
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Dosage (Strength)
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340mcg / 12mcg (60 doses / inhaler)
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Pregnancy
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Consult Doctor
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Brands
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Duaklir Pressair
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Protein binding
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Aclidinium Bromide: Approximately 87% Formoterol Fumarate Dihydrate: 61-64%
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PubChem CID
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Aclidinium Bromide: 11625033 Formoterol Fumarate Dihydrate: 11523773
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MedlinePlus
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Not listed
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ChEBI
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Aclidinium Bromide: 65344 Formoterol Fumarate Dihydrate: 408174
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ATC code
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R03AL03
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DrugBank
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Aclidinium Bromide: DB08897 Formoterol Fumarate Dihydrate: DB00983
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KEGG
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Aclidinium Bromide: D08837 Formoterol Fumarate Dihydrate: D07990
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Routes of administration
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Inhalation
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Directions
Inhale one inhalation of Duaklir Pressair twice daily as directed by your healthcare provider.
Duaklir Pressair is not a rescue inhaler. It must be used every day for the full effect.
Ingredients
Duaklir Pressair contains two different active ingredients: aclidinium 400 mcg and formoterol 12 mcg.
Interactions
Duaklir Pressair may interact with the following medications:
- Anticholinergic Agents
- Advair Diskus
- AirDuo Respiclick
- Anoro Ellipta
- Bevespi Aerosphere
- Breo Ellipta
- Carvedilol
- Cocaine
- Dulera
- Eluxadoline
- Foradil Aerolizer
- Glycopyrrolate
- Inderal
- Ipratropium
- Labetalol
- Levosulpiride
- Linezolid
- Loxapine
- Methacholine
- Nadolol
- Penbutolol
- Pindolol
- Potassium Chloride
- Potassium Citrate
- Propranolol
- Secretin
- Serevent Diskus
- Sotalol
- Stiolto Respimat
- Striverdi Respimat
- Symbicort
- Tiotropium
- Trelegy Ellipta
- Umeclidinium
Cautions
Duaklir Pressair is not indicated for the treatment of asthma. It also should not be used for acute bronchospasm. It is a maintenance inhaler and must be taken each day for full effect.
Tell your doctor if you have a history of heart disease, seizure disorders, thyroid disorders, or diabetes mellitus.
This medication can worsen narrow-angle glaucoma.
Side Effects
Duaklir Pressair side effects may include:
- Arthralgia
- Back pain
- Bronchospasm
- Cough
- Dizziness
- Headache
- Increased kidney enzymes
- Influenza
- Insomnia
- Limb pain
- Muscle spasm
- Musculoskeletal pain
- Oropharyngeal pain
- Pruritus
- Sinusitis
- Skin rash
- Tooth Abscess
- Upper respiratory tract infection
- Urinary tract infection
- Urticaria
- Xerostomia
References
- Duklaior Pressair [package insert]. Morrisville, NC: AstraZeneca; 2019.
Frequently Asked Questions about Duaklir Pressair
What is Duaklir Pressair?
Duaklir Pressair is a prescription medication that combines two active ingredients, Aclidinium Bromide and Formoterol Fumarate Dihydrate. It is used to manage chronic obstructive pulmonary disease (COPD) in adults.
How does Duaklir Pressair work?
Duaklir Pressair contains two bronchodilators, Aclidinium Bromide and Formoterol Fumarate Dihydrate. Aclidinium Bromide helps to relax the airways, making it easier to breathe, while Formoterol Fumarate Dihydrate helps to open the air passages, providing relief from COPD symptoms.
What is Duaklir Pressair used for?
Duaklir Pressair is primarily used to manage the symptoms of COPD, which may include shortness of breath, wheezing, coughing, and chest tightness. It is not a rescue inhaler and should not be used to treat sudden breathing problems.
Is Duaklir Pressair a rescue medication for COPD exacerbations?
No, Duaklir Pressair is not intended as a rescue medication for sudden COPD exacerbations. It is a maintenance medication designed to help control and prevent symptoms of COPD over the long term. If you experience sudden worsening of COPD symptoms, you should use your prescribed rescue inhaler as directed by your healthcare provider.
How should I use Duaklir Pressair?
Duaklir Pressair comes in inhalation powder form and is typically taken twice daily, as prescribed by your healthcare provider. It should be inhaled orally, and you should follow the instructions provided with the medication carefully.
Are there any potential side effects of Duaklir Pressair?
Like all medications, Duaklir Pressair may cause side effects. Common side effects may include headache, cough, dry mouth, and throat irritation. It's essential to discuss any side effects with your healthcare provider.
Can I use Duaklir Pressair if I have allergies or other medical conditions?
You should inform your healthcare provider about any allergies or medical conditions you have before starting Duaklir Pressair. Your healthcare provider will consider your medical history to determine if Duaklir Pressair is safe and appropriate for you.
Can Duaklir Pressair be used during pregnancy or while breastfeeding?
It is crucial to discuss the use of Duaklir Pressair with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding. They can assess the potential risks and benefits and provide guidance on the best course of action.
Can I continue using my other COPD medications alongside Duaklir Pressair?
You should consult your healthcare provider before combining Duaklir Pressair with other COPD medications or inhalers. They can help you create a comprehensive treatment plan that meets your specific needs.
How long should I use Duaklir Pressair?
The duration of Duaklir Pressair use will be determined by your healthcare provider. It is generally used as a long-term maintenance medication to manage COPD symptoms effectively.
About Dr. Conor Sheehy (Page Author)
Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 13221