What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Duac (Clindamycin phosphate, benzoyl peroxide)
Also Known as Clindoxyl
Prescription Required
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Product Details
Description
Duac (clindamycin phosphate and benzoyl peroxide) Gel, 1.2%/5% is a gel used to treat inflammatory acne.
Duac Gel has not shown to be more effective than benzoyl peroxide alone in the same vehicle for the treatment of non-inflammatory acne.
Fact Table
Formula
C18H34ClN2O8PS.C14H10O4
License
US DailyMed
Bioavailability
-
Legal status
Rx-Only
Chemical Name
Clindamycin/benzoyl peroxide
Elimination half-life
9 hours
Dosage (Strength)
3%/1% Gel, 1%/5% Gel
Pregnancy
Consult Doctor
Brands
Duac
Protein binding
60-94%
PubChem CID
57383951
MedlinePlus
a603021
ChEBI
-
ATC code
D10AE51
DrugBank
-
KEGG
D10602
Routes of administration
Topical
Directions
Follow the instructions and read the package insert that comes with your Duac Gel prescription. Your doctor or pharmacist can help you with any questions or concerns you may have about the medication.
Duac Gel is available in a gel consisting of clindamycin phosphate (a lincosamide antibacterial) and benzoyl peroxide.
Duac Gel is for use on the skin only. Do not get the gel in your mouth, eyes, or vagina. Do not apply it to scratches or cuts on the skin.
First, gently wash your face with a mild soap. Rinse your face with warm water and dry the skin by patting. It is recommended to apply a thin layer of Duac Gel to the face one time a day in the evening. Wash your hands with soap and water after applying the gel.
Ingredients
Each gram of gel consists of 12 mg of clindamycin phosphate (a lincosamide antibacterial) and 50 mg of benzoyl peroxide.
Duac Gel also contains inactive ingredients such as carbomer homopolymer (type C), dimethicone, disodium lauryl sulfosuccinate, edetate disodium, glycerin, methylparaben, poloxamer 182, purified water, silicon dioxide, and sodium hydroxide.
Contraindications
Do not use Duac Gel if you are allergic to clindamycin, benzoyl peroxide, or any of the other ingredients contained in the medication.
Do not use Duac Gel if you have regional enteritis, ulcerative colitis, or antibiotic-associated colitis.
Cautions
- Before you begin treating your acne with Duac topical gel, talk to your doctor about:
- Your allergies
- Your medications, including other topical medications
- Your health conditions
- Your breastfeeding or pregnancy status
- Duac Gel can cause colitis that may be severe or fatal. Contact your doctor immediately if you develop diarrhea, bloody diarrhea, or any other effects.
- Duac Gel can make you more sensitive to ultraviolet light from the sun, tanning beds, and sun lamps. Avoid prolonged sun exposure after applying the gel. Use sunscreen and wear protective clothing when going out in the sun.
Side Effects
The most common side effects caused by Duac acne gel include skin redness, peeling, dryness, and burning. Contact your doctor right away if you develop side effects that worry you or persist.
Reference:
Duac (clindamycin phosphate and benzoyl peroxide) Gel, 1.2%/5% for topical use. Research Triangle Park, NC: Stiefel Laboratories, Inc.; 2013.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 9704
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