Description
Dicloxacillin is a prescription antibiotic that your doctor can prescribe for certain types of infections including skin infections and infections of prosthetic joints. It is typically started in the hospital as an infusion before someone is converted to the oral formulation.
Dicloxacillin is an antibiotic that works by disrupting the formation of bacterial cell walls. Cell walls protect bacteria from the environment, and by blocking the formation of cell walls, the bacteria die, helping to treat the infection.
Fact Table |
Formula |
C19H17Cl2N3O5S |
License |
US FDA |
Bioavailability |
60 to 80% |
Legal status |
Rx-only |
Chemical Name |
Dicloxacillin |
Elimination half-life |
0.7 hours |
Dosage (Strength) |
250mg, 500mg |
Pregnancy |
Consult Doctor |
Brands |
Generic |
Protein binding |
98% |
PubChem CID |
18381 |
MedlinePlus |
a685017 |
ChEBI |
4511 |
ATC code |
J01CF01 |
DrugBank |
DB00485 |
KEGG |
D02348 |
Routes of administration |
Oral |
Directions
Take dicloxacillin exactly as directed by your doctor. The directions will be different depending on what is being treated.
The usual dosage for prosthetic joint infections is 500 mg three to four times daily for at least three months. Some people may need to continue indefinitely.
The usual dosage for skin infections is 250-500 mg three to four times daily for 5-7 days.
Ingredients
The active ingredient in dicloxacillin is dicloxacillin since it is a generic medication.
Interactions
The most common drug-drug interactions with this drug can include:
- Acemetacin
- Aminoglycosides
- BCG (intravesical)
- BCG vaccine
- Brivaracetam
- CarBAMazepine
- Carisoprodol
- Cholera vaccine
- CloZAPine
- DiazePAM
- Dichlorphenamide
- Etravirine
- Fosphenytoin-Phenytoin
- Hormonal contraceptives
- Immune checkpoint inhibitors
- Lactobacillus and Estriol
- Methotrexate
- Mycophenolate
- Nelfinavir
- NiMODipine
- Omeprazole
- Ospemifene
- Probenecid
- Selpercatinib
- Sirolimus
- Sodium picosulfate
- Tacrolimus
- Tetracyclines
- Typhoid vaccine
- Ubrogepant
- Vitamin K antagonists
- Voriconazole
Tell your doctor and pharmacist if you experience any of the above side effects while taking this drug.
Cautions
Tell your doctor if you have a history of kidney or liver problems before starting this drug.
Side Effects
Dicloxacillin side effects may include:
- Abdominal pain
- Anemia
- Diarrhea
- Eosinophilia
- Fever
- Hematuria
- Hemolytic anemia
- Hepatotoxicity
- Hypersensitivity reaction
- Increased blood urea nitrogen
- Increased liver enzymes
- Increased serum creatinine
- Leukopenia
- Nausea
- Neutropenia
- Prolonged prothrombin time
- Psudomembranous colitis
- Seizure
- Skin rash
- Thrombocytopenia
- Vaginitis
- Vomiting
References
Dicloxacillin. Princeton, NJ: Sandoz, Inc.; 2018.
Frequently Asked Questions about Dicloxacillin
What is Dicloxacillin?
Dicloxacillin is an antibiotic medication that belongs to the penicillin class of antibiotics. It is used to treat various bacterial infections by inhibiting the growth of bacteria.
What conditions does Dicloxacillin treat?
Dicloxacillin is commonly prescribed to treat bacterial infections such as skin and soft tissue infections, respiratory tract infections, and certain types of staphylococcal infections.
How does Dicloxacillin work?
Dicloxacillin works by interfering with the formation of bacterial cell walls. It weakens and destroys the cell walls of bacteria, ultimately leading to their death.
Is Dicloxacillin effective against all types of infections?
No, Dicloxacillin is specifically effective against infections caused by bacteria that are sensitive to this antibiotic. It does not treat viral infections like the common cold or flu.
What are the common side effects of Dicloxacillin?
Common side effects of Dicloxacillin may include nausea, vomiting, diarrhea, abdominal pain, skin rashes, and itching. It's essential to report any severe or unusual side effects to your healthcare provider.
How should I take Dicloxacillin?
Dicloxacillin is usually taken orally, with or without food, as directed by your healthcare provider. Follow the prescribed dosage and complete the full course of treatment, even if your symptoms improve before it's finished.
Can I drink alcohol while taking Dicloxacillin?
It is generally advisable to avoid alcohol while taking antibiotics, including Dicloxacillin, as alcohol can interfere with the effectiveness of the medication and may exacerbate side effects.
Is Dicloxacillin safe during pregnancy or while breastfeeding?
If you are pregnant, planning to become pregnant, or breastfeeding, it's crucial to discuss the use of Dicloxacillin with your healthcare provider. They can evaluate the potential risks and benefits in your specific situation.
What should I do if I miss a dose of Dicloxacillin?
If you miss a dose, take it as soon as you remember. However, if it's close to the time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not double dose to make up for a missed one.
Can Dicloxacillin interact with other medications?
Dicloxacillin can interact with certain medications, including blood thinners and oral contraceptives. Inform your healthcare provider about all the medications you are taking to prevent potential drug interactions.
About Dr. Conor Sheehy (Page Author)
Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 13599