What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Dibenzyline (Phenoxybenzamine)
We don't have this brand product yet!
Sign up to get exclusive coupon discounts and be the first to be notified when we have this product available.
Generic Equivalent - Dibenzyline (Phenoxybenzamine)
Prescription Required
You'll have option to make 4 interest-free payments by credit card once your order is confirmed using
-
Product Details
Description
Dibenzyline is a non-selective alpha-adrenergic antagonist. It is commonly used to treat high blood pressure (hypertension) and excessive sweating associated with pheochromocytoma, a rare tumor of the adrenal glands.
High blood pressure is a common condition that is a significant contributor to deadly heart conditions like heart attack, arrhythmia, and atherosclerosis. Blood pressure can go unnoticed for years, and it is important to appropriately treat it.
Phenoxybenzamine blocks alpha-adrenergic receptors, preventing norepinephrine from constricting blood vessels. This results in blood vessel relaxation, lowering blood pressure, and reducing sweating.
Fact Table
Formula
C18H22ClNO
License
US FDA
Bioavailability
20-30% (oral)
Legal status
Prescription only (?)
Chemical Name
N-(2-Chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzenemethanamine
Elimination half-life
24 hours
Dosage (Strength)
10 mg capsules
Pregnancy
Consult a doctor
Brands
Dibenzyline
Protein binding
90-95%
PubChem CID
4763
MedlinePlus
a682250
ChEBI
CHEBI:45081
ATC code
C04AX02
DrugBank
DB00925
KEGG
D08359
Routes of administration
Oral
Directions
The usual starting dosage is 10 mg by mouth twice daily.
If needed, the dosage can be increased every other day to a target of 20-40 mg two to three times daily.
Ingredients
The active ingredient in Dibenzyline is phenoxybenzamine.
Interactions
Tell your doctor and pharmacist if you are taking any of the following drugs:
- Acebutolol
- Alprenolol
- Asenapine
- Atenolol
- Betaxolol
- Bevantolol
- Bisoprolol
- Bucindolol
- Carteolol
- Carvedilol
- Celiprolol
- Dilevalol
- Esmolol
- Labetalol
- Levobunolol
- Mepindolol
- Melphalan
- Metipranolol
- Metoprolol
- Nadolol
- Nebivolol
- Oxprenolol
- Penbutolol
- Pindolol
- Propranolol
- Silodosin
- Sotalol
- Tadalafil
- Talinolol
- Tamsulosin
- Tertatolol
- Timolol
- Vardenafil
Cautions
Tell your doctor before starting Dibenzyline if you have a history of cardiovascular disease, renal impairment, or conditions affecting blood pressure regulation.
This drug can cause significant drops in blood pressure, especially upon standing (orthostatic hypotension), leading to dizziness or fainting.
If you feel dizzy when standing, rise slowly from sitting or lying positions to reduce the risk of these effects. Tell your doctor if you experience these side effects because it might mean your dose is too high.
Regular monitoring of blood pressure and other vital signs is essential during treatment with phenoxybenzamine.
Side Effects
The most common side effects of this drug may include:
- Absence of ejaculation
- Dizziness
- Fatigue
- Hypotension
- Miosis
- Nasal congestion
- Nausea
- Seizure (serious)
- Sedated
- Somnolence
- Tachyarrhythmia
- Vomiting
- Xerostomia
References
Dibenzyline [package insert].Oakville, Ontario: WellSpring; March 2008.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 2717
-
Product Reviews
