What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Diacomit (Stiripentol)
Prescription Required
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Product Details
Description
Diacomit (stiripentol) is a prescription medication for treating seizures due to Dravet syndrome in patients who are at least 6 months old, weigh at least 7 kg, and are taking clobazam.
Diacomit comes in 250 mg and 500 mg oral capsules and oral suspension.
Fact Table
Formula
C14H18O3
License
US FDA, EMA
Bioavailability
Varies with formulation
Legal status
Prescription only (Rx)
Chemical Name
(RS)-4,4-Dimethyl-1-[3,4-(methylenedioxy)phenyl]-1-penten-3-ol
Elimination half-life
4.5 to 13 hours
Dosage (Strength)
250 mg, 500 mg capsules or granules
Pregnancy
Consult a doctor
Brands
Diacomit
Protein binding
96%
PubChem CID
68740
MedlinePlus
a619048
ChEBI
9243
ATC code
N03AX17
DrugBank
DB09048
KEGG
D01359
Routes of administration
Oral
Directions
You or your child should take Diacomit exactly as prescribed by the doctor. The doctor will determine an appropriate Diacomit dosage based on weight and age.
Do not open or break the capsules; swallow the capsules whole with a full glass of water; take with a meal.
The powder for oral suspension should be mixed in a glass of water; take immediately after mixing and during a meal.
Store Diacomit capsules and oral suspension in a dry place, protected from light, between 20oC and 25oC (68oF and 77oF). Keep out of reach of children.
For additional instructions for use, refer to the medication guide that accompanies the Diacomit prescription.
If you have any questions or concerns, contact your or your child’s doctor or pharmacist.
Ingredients
The active ingredient in Diacomit is stiripentol.
Inactive ingredients in the capsules include erythrosine (250 mg capsule only), gelatin, indigotine (250 mg capsule only), magnesium stearate, povidone, sodium starch glycolate, and titanium dioxide.
Inactive ingredients in the oral suspension include aspartame, carmellose sodium, erythrosine, glucose, hydroxyethylcellulose, povidone, sodium starch glycolate, sorbitol, titanium dioxide, and fruit flavor (acacia, Bergamot oil, hypromellose, maltodextrin, sorbitol, and vanillin).
Contraindications
According to the most recent Prescribing Information, there are no contraindications to taking Diacomit.
Cautions
- Before you or your child starts taking Diacomit, tell the doctor about:
- All the prescription and over-the-counter medications you or your child takes
- Your or your child’s allergies
- Your or your child’s current health problems and past medical history
- Your or your child’s pregnancy or breastfeeding status
- Diacomit is associated with the following warnings and precautions:
- Drowsiness/excessive sleepiness
- Appetite and weight loss
- Low neutrophil and platelet counts
- Increased risk of seizure frequency and status epilepticus if discontinued abruptly; Diacomit should be withdrawn gradually
- The oral suspension contains phenylalanine, which may be associated with risks in patients with phenylketonuria
- Suicidal behavior and ideation
Side Effects
Drowsiness/excessive sleepiness, appetite loss, weight loss, agitation, impaired coordination, decreased muscle tone, nausea, tremor, slurred speech, and trouble sleeping are some Diacomit side effects. Other side effects may also occur.
Immediately notify a doctor about any side effects that bother you or your child or side effects that won’t go away.
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Reference
- Diacomit. Beauvais, France: Biocodex; 2022.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 14612
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