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Denamarin (Nutramax)

What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

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  • Product Details

    Description

    Denamarin is a supplement for liver health in dogs and cats.

    Denamarin is available in the following formulations:

    • Chewable tablets for dogs of every size
    • Coated tablets for small dogs
    • Coated tablets for large dogs
    • Coated tablets for cats

    Fact Table

    Formula

    S-Adenosylmethionine: C15H22N6O5S
    Silybin (from milk thistle): C25H22O10

    License

    OTC (veterinary nutraceutical)

    Bioavailability

    Improved with enteric coating; varies by species

    Legal status

    OTC (veterinary use only)

    Chemical Name

    S-Adenosylmethionine (SAMe) + Silybin (complexed with phosphatidylcholine)

    Elimination half-life

    SAMe: ~1.7 hours (in dogs); Silybin: ~6–8 hours

    Dosage (Strength)

    90 mg, 225 mg, 425 mg, and 625 mg SAMe per tablet with silybin complex

    Pregnancy

    Veterinary discretion advised; no human pregnancy data

    Brands

    Denamarin (Nutramax), Denamarin Advanced

    Protein binding

    Not well defined (supplement)

    PubChem CID

    SAMe: 34755
    Silybin: 31553

    MedlinePlus

    Not applicable (veterinary supplement)

    ChEBI

    SAMe: CHEBI:16865
    Silybin: CHEBI:9144

    ATC code

    Not assigned (non-drug veterinary product)

    DrugBank

    SAMe: DB00118
    Silybin: DB14009

    KEGG

    SAMe: C00019
    Silybin: Not listed

    Routes of administration

    Oral (tablet, chewable)

    Directions

    Administer Denamarin to your dog or cat as directed by your veterinarian. Your veterinarian will determine an appropriate dosage for your pet.

    Talk to your veterinarian about any questions or concerns you have.

    Ingredients

    SAMe (S-Adenosylmethionine) is found in Denamarin.

    Contraindications

    Contraindications not found on Denamarin’s website.

    Cautions

    • Before you administer Denamarin to your dog or cat, tell your veterinarian about your pet’s:
      • Medications
      • Allergies
      • Current health problems and past medical history
      • Status of pregnancy, breeding, or lactating

    Side Effects

    According to Denamarin’s website, there are no known side effects of the medication.

    Contact your veterinarian right away if your dog or cat has side effects that become bothersome or won’t go away.

    You can buy Denamarin right here!



    Dr Savannah Muncy
    About Dr. Savannah Muncy (Page Author)


    Dr. Muncy (PharmD) studied science and education as an undergraduate before attending the Appalachian College of Pharmacy where she completed her PharmD in three years. She is currently using her pharmacy and healthcare expertise to write medical content for clients all around the world. She is focused on delivering the most current, accurate, and engaging information to healthcare professionals and patients. Read More....


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13937

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