What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Clomid (Clomiphene)
Also Known as Comid, Serophene
Prescription Required
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Product Details
Description
CLOMID (clomiphene) is a medication prescribed to treat ovulatory dysfunction in women desiring to become pregnant. CLOMID is most likely to be effective in patients suffering from amenorrhea-galactorrhea syndrome, psychogenic amenorrhea, post-oral-contraceptive amenorrhea, and polycystic ovary syndrome (PCOS).
CLOMID works by binding to estrogen receptors in the hypothalamus, an area of the brain responsible for releasing cyclic hormones. By binding to estrogen receptors, clomiphene prevents the natural recycling of estrogen, which causes other hormones involved in fertility to surge and the release of eggs from the ovaries.
Fact Table
Formula
C26H28ClNO
License
-
Bioavailability
More than 90%
Legal status
Rx-Only
Chemical Name
Clomifene
Elimination half-life
5–6 days
Dosage (Strength)
50mg
Pregnancy
Not recommended
Brands
Clomid
Protein binding
Not Available
PubChem CID
2800
MedlinePlus
a682704
ChEBI
3752
ATC code
G03GB02
DrugBank
DB00882
KEGG
D07726
Routes of administration
By mouth (tablets)
Directions
The usual starting dose is to take one CLOMID 50 mg tablet by mouth daily for five days. Begin taking CLOMID on or around the fifth day of the menstrual cycle if bleeding is induced by progestin or spontaneously occurs before therapy. Treatment may begin at any time if there has been no recent uterine bleeding.
In some patients, the dose may be increased to CLOMID 100 mg by mouth once daily for five days if ovulation does not occur with the CLOMID 50 mg once daily dose. For patients who experience adverse effects, the dose may be decreased from 12.5 to 25 mg by mouth once daily.
A cycle of CLOMID may be repeated 30 days after the prior cycle.
CLOMID should not be taken for longer than six cycles.
Ask your doctor when to take CLOMID and how it should be used. Take CLOMID exactly as prescribed by your doctor and do not deviate from those instructions unless your doctor changes the prescription.
Ingredients
The active ingredient in CLOMID is clomiphene citrate, which is a mixture of zuclomiphene and enclomiphene.
Cautions
Visual disturbances may occur with CLOMID therapy. These symptoms may be irreversible in some cases. Use caution operating vehicles or heavy machinery while taking CLOMID.
Tell your doctor immediately if you experience discomfort, distension, weight gain, or pelvic pain while taking CLOMID, as this may be a sign of ovarian enlargement.
Pregnancies that occur while taking CLOMID have a higher likelihood of producing multiple pregnancy.
CLOMID should not be taken if you are currently pregnant and may be harmful to the fetus.
Side Effects
Some of the most common adverse effects of CLOMID may include:
- Abnormal Uterine Bleeding
- Blurred vision and other visual symptoms
- Breast Discomfort
- Headache
- Nausea
- Ovarian Enlargement
- Vasomotor Flushes
- Vomiting
Speak with your doctor or pharmacist for a complete list of side effects.
References
- Clomid [package insert]. Bridgewater, NJ: Sanofi-Aventis; 2012.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 1419
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