Description
Cefepime Injection (Cefepime) is a fourth-generation cephalosporin antibiotic used to treat a wide range of bacterial infections, including pneumonia, urinary tract infections, and skin infections. It can be used against susceptible strains of bacteria in various settings, such as hospitals and long-term care facilities.
Fact Table |
Formula |
C19H24N6O5S2 |
License |
US DailyMed |
Bioavailability |
100% |
Legal status |
Rx-only |
Chemical Name |
Cefepime |
Elimination half-life |
2 hours |
Dosage (Strength) |
1g, 2g |
Pregnancy |
Consult Doctor |
Brands |
Cefepime Injection (Generic) |
Protein binding |
21% |
PubChem CID |
5479537 |
MedlinePlus |
a698021 |
ChEBI |
478164 |
ATC code |
J01DE01 |
DrugBank |
DB01413 |
KEGG |
D02376 |
Routes of administration |
Intravenous |
Directions
Cefepime is available in vials for intravenous (IV) or intramuscular (IM) administration. The cefepime injection dosage depends on the type and severity of the infection, ranging from 0.5 g to 2 g, usually administered every 12 hours for 7 to 10 days.
This medication is typically given in a hospital or clinic by a trained healthcare professional. Consult your healthcare provider for the specific cefepime injection dosage. Each vial is for single use only, and any remaining cefepime for injection should be discarded properly.
Ingredients
Each vial of Cefepime Injection contains cefepime hydrochloride equivalent to the selected cefepime for injection dosage.
Contraindications
Do not use Cefepime Injection if you are allergic to cefepime or any other cephalosporin or penicillin antibiotics.
Cautions
- Before you start using Cefepime Injection, tell your doctor:
- About any allergies you have, especially to penicillin or other cephalosporins
- About any medications you take, including prescription, over-the-counter medications, and herbal products
- About any health conditions you have, such as kidney or liver problems and digestive conditions
- If you are pregnant or plan to become pregnant
- If you are nursing or plan to nurse your baby
- Cefepime may cause a severe intestinal condition called Clostridium difficile-associated diarrhea. Contact your doctor right away if you experience persistent diarrhea, abdominal pain, or blood in your stool.
- Cefepime should only be used for infections caused by susceptible bacteria. Using it otherwise may lead to antibiotic resistance.
- Cefepime should only be used for bacterial infections. It is not suitable for viral or fungal infections.
- Cefepime may cause diarrhea or more serious intestinal conditions that may occur even two or more months after treatment. Contact your physician if serious symptoms of diarrhea develop.
- Serious neurological events are possible while using Cefepime, such as seizures and encephalopathy. Consult a healthcare provider immediately if you experience symptoms like confusion, hallucinations, or unusual muscle movements.
- The use of cefepime may increase the risk of problems with blood clots. Certain people, such as those with kidney or liver problems, may need vitamin K.
- If you're having certain blood tests while on Cefepime, they might show different results. Always tell your doctor or the lab that you're taking Cefepime.
- Store Cefepime Injection at controlled room temperature, away from light and moisture.
Side Effects
The most common side effects of Cefepime Injection include local reactions at the injection site, diarrhea, nausea, vomiting, and rash. More serious side effects may include seizures, changes in mental status, and allergic reactions. Call your doctor right away if you experience any severe or persistent side effects.
References:
- Cefepime Injection Prescribing Information. Lake Forest, IL: Hospira, Inc.; 2021.
- Maxipime (cefepime injection) Dosage Information. DailyMed. Accessed August 9, 2023.
About Dr. Gerardo Sison (Page Author)
Dr. Sison graduated with honors from the University of Florida. He began his career in pharmacy counseling patients in a community setting and later served in hospitals and clinics. He has also worked in medication therapy management services. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 13830