What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Cabometyx (Cabozantinib)
Prescription Required
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Product Details
Description
Cabometyx is a medication used to treat advanced kidney cancer, liver cancer, and differentiated thyroid cancer.
Cabometyx comes in 20 mg, 40 mg, and 60 mg oral tablets.
Directions
Take Cabometyx exactly as your doctor has prescribed. If you have any questions or concerns, talk to your doctor or pharmacist.
Your doctor will determine an appropriate dose for you. Generally, patients take one tablet by mouth once daily.
Ingredients
Cabozantinib is the active ingredient in Cabometyx. Microcrystalline cellulose, lactose anhydrous, hydroxypropyl cellulose, croscarmellose sodium, colloidal silicon dioxide, and magnesium stearate are inactive ingredients included.
Contraindications
According to the most recent Prescribing Information, there are no contraindications, or no conditions in which a person cannot take Cabometyx.
Cautions
- Before you begin receiving treatment with Cabometyx, tell your doctor:
- About all the prescription and over-the-counter medications you take
- About your allergies
- About your current health conditions and past medical history
- If you are pregnant or breastfeeding
- Cabometyx should not be administered in patients with a recent history of hemorrhage.
- Gastrointestinal perforation and fistulas can occur during treatment with Cabometyx.
- The risk of thrombotic events (i.e., heart attack, blood clots) is increased with Cabometyx use.
- Cabometyx can cause high blood pressure that can become dangerously high. Cabometyx should not be given to patients with uncontrolled high blood pressure.
- Cabometyx can cause diarrhea.
- Cabometyx can cause hand-foot syndrome, or redness and swelling of the palms of the hands and soles of the feet.
- Cabometyx can cause liver toxicity, especially when taken with nivolumab.
- Cabometyx can cause adrenal insufficiency.
- Cabometyx can cause protein in the urine.
- Cabometyx can cause osteonecrosis of the jaw which can result in jaw pain, bone infection, bone inflammation, bone erosion, tooth or periodontal infection, toothache, gingival ulceration or erosion, and slow healing of the mouth or jaw after dental surgery.
- Cabometyx can cause wound complications, including impaired wound healing.
- Cabometyx can cause Reversible Posterior Leukoencephalopathy Syndrome (RPLS), a condition that results in headaches, vision problems, mental changes, seizures, and brain swelling.
- Cabometyx can cause thyroid problems.
- Cabometyx can cause low calcium levels in the blood.
- Cabometyx may cause harm to an unborn baby. Effective birth control methods should be used during treatment with Cabometyx and for 4 months after taking the last dose.
Side Effects
Diarrhea, fatigue, hand-foot syndrome, decreased appetite, high blood pressure, nausea, vomiting, weight loss, and constipation are common Cabometyx side effects. However, these are not the only side effects that can occur. Call your doctor right away if you have side effects that bother you or won’t go away.
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Reference
Cabometyx. Alameda, CA: Exelixis, Inc.; 2022.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13950
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