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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Binosto (Alendronate Sodium)
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Product Details
Description
Your doctor may prescribe Binosto to treat osteoporosis in postmenopausal women or increase bone mass in men with osteoporosis.
Binosto works in cells of the bone called osteoclasts. Under normal conditions, osteoclasts are always breaking down bone, and osteoblasts rebuild bone. In adults with osteoporosis, Binosto attaches to osteoclasts and prevents them from breaking down bone. Binosto incorporated into the matrix of the bone, causing an increase in bone mass over time.
Fact Table
Formula
C4H13NO7P2
License
US FDA, EU EMA
Bioavailability
0.6%
Legal status
Rx-only
Chemical Name
Alendronic acid
Elimination half-life
126 months
Dosage (Strength)
70mg
Pregnancy
Not Recommended
Brands
Fosamax, Binosto
Protein binding
78%
PubChem CID
2088
MedlinePlus
a601011
ChEBI
2567
ATC code
M05BA04
DrugBank
DB00630
KEGG
D07119
Routes of administration
By mouth
Directions
Binosto is available in 70 mg effervescent tablets. Dissolve one Binosto 70 mg tablet in 4 oz of room temperature water and drink it once weekly. Wait five minutes for the tablets to dissolve, and then stir the solution for 10 seconds and consume the content.
Ingredients
The active ingredient in Binosto is alendronate sodium.
Cautions
Tell your doctor if you have any abnormalities of the esophagus or cannot stand or sit upright for 30 minutes after taking this medication.
Use caution if you have a history of low calcium in the blood.
Do not use Binosto if you have a dietary sodium restriction.
Do not eat for 30 minutes after taking Binosto.
Do not lie down for 30 minutes after taking Binosto.
Interactions
Tell your doctor and pharmacist about all medications you are taking, including prescription, over-the-counter (OTC), herbals, and supplements.
Common drug-drug interactions with Binosto may include:
- Aminoglycosides
- Aspirin
- Ibuprofen
- Naproxen
- Parathyroid hormone
- Proton pump inhibitors
Side Effects
Common side effects of Binosto may include:
- Abdominal pain
- Acid regurgitation
- Atypical femur fractures
- Constipation
- Decreased serum phosphate
- Diarrhea
- Dyspepsia
- Headache
- Hypocalcemia
- Musculoskeletal pain
- Nausea
- Osteonecrosis of the jaw
References
Binosto [package insert]. San Antonio, TX: Mission Pharmacal; 1995.
Frequently Asked Questions about Binosto (Alendronate Sodium)
What is Binosto (Alendronate Sodium)?
Binosto is a brand name for the medication Alendronate Sodium. It belongs to a class of drugs known as bisphosphonates and is primarily used to treat and prevent osteoporosis in postmenopausal women and men.
How does Alendronate Sodium work?
Alendronate Sodium helps to increase bone density and reduce the risk of fractures by slowing down the process of bone loss. It inhibits the breakdown of bone tissue, thereby making bones stronger.
Who should take Binosto?
Binosto is typically prescribed for postmenopausal women and men at risk of osteoporosis, especially those with a history of fractures or low bone mineral density. Your doctor will determine if it's the right treatment for you.
How is Binosto (Alendronate Sodium) taken?
Binosto comes in the form of an effervescent tablet that should be dissolved in a glass of water and taken on an empty stomach in the morning. It's important not to lie down for at least 30 minutes after taking it to prevent irritation of the esophagus.
What are the common side effects of Binosto?
Common side effects of Alendronate Sodium may include stomach upset, heartburn, difficulty swallowing, and bone, muscle, or joint pain. It's crucial to follow the dosing instructions carefully to minimize side effects.
Are there any serious side effects associated with Binosto?
Yes, there can be serious side effects, such as severe gastrointestinal problems, including esophageal ulcers or narrowing. It's essential to report any new or unusual symptoms to your healthcare provider promptly.
Can Binosto interact with other medications?
Alendronate Sodium can interact with certain medications, so it's important to inform your healthcare provider about all the drugs and supplements you are taking, including calcium and vitamin D supplements.
How long should I take Binosto?
The duration of Binosto treatment depends on your individual risk factors for osteoporosis and your doctor's recommendations. Some individuals may need to take it for several years, while others may require lifelong treatment.
Can I take Binosto if I am pregnant or breastfeeding?
Binosto is generally not recommended for pregnant or breastfeeding individuals, as its safety in these situations has not been established. Discuss your options with your healthcare provider if you are pregnant or nursing.
How often should I have bone density tests while taking Binosto?
Your doctor will determine the frequency of bone density tests based on your specific condition. Typically, these tests are performed periodically to monitor the effectiveness of treatment.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13281
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