What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Biaxin (Clarithromycin)
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Product Details
Description
Biaxin (clarithromycin) is a macrolide antibiotic that's used to treat certain bacterial infections of the lungs, skin, ears, sinuses, and throat. It's also used with other medications to treat a type of bacteria in the stomach called Helicobacter pylori (H. pylori). Further, it's used to treat and prevent disseminated Mycobacterium avium complex (MAC) disease in patients with advanced human immunodeficiency virus (HIV).
Biaxin is available in the following dosage forms and strengths:
- Biaxin Filmtabs: 250 mg, 500 mg
- Biaxin XL Filmtabs: 500 mg
- Biaxin Granules for Oral Suspension: 125 mg/5 mL, 250 mg/5 mL
Fact Table
Formula
C38H69NO13
License
US DailyMed, EU EMA
Bioavailability
50%
Legal status
Rx-only
Chemical Name
Clarithromycin
Elimination half-life
3–4 h
Dosage (Strength)
500mg
Pregnancy
Consult Doctor
Brands
Biaxin
Protein binding
Low binding
PubChem CID
84029
MedlinePlus
a692005
ChEBI
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ATC code
J01FA09
DrugBank
DB01211
KEGG
D00276
Routes of administration
By mouth
Directions
The instructions that come with your prescription should be carefully followed. Take Biaxin as prescribed by your doctor. You should finish your course of antibiotics, even if you start to feel better. Talk to your doctor about any questions or concerns you have about the medication.
Dosing:
If taking Biaxin Filmtabs, the dosage generally ranges from 250 mg to 500 mg by mouth every 12 hours, with or without food.
If taking Biaxin XL Filmtabs, the dosage is generally two 500 mg tablets (1,000 mg total) by mouth every 24 hours, with food. Swallow the tablets whole; do not crush or chew them.
If taking the oral suspension, shake the bottle well before using and measure out the required volume needed using a dropper or measuring cup. You may take the oral suspension with or without food. Store the suspension at room temperature between 59°F and 86°F. Discard any remainder after 14 days.
The dose of Biaxin may need to be adjusted in patients with kidney problems.
The duration of treatment is generally seven to 14 days.
Ingredients
The active ingredient in Biaxin is clarithromycin. Biaxin also contains many inactive ingredients that vary between the different dosage forms.
Contraindications
Do not take Biaxin if you are allergic to clarithromycin, erythromycin, or any of the other macrolides.
Do not take Biaxin if you have a history of liver problems or cholestatic jaundice caused by prior use of Biaxin.
Do not take the following medications with Biaxin as dangerous drug interactions can occur:
- Cisapride
- Pimozide
- Astemizole
- Terfenadine
- Ergotamine or dihydroergotamine
- Colchicine (if you have kidney or liver problems)
Ask your doctor if you are unsure whether or not you take any of these medications.Cautions
- Before you begin treatment with Biaxin, be sure to discuss the following with your doctor:
- Any prescription and over-the-counter medications you take
- Your allergies
- Your health history and medical problems
- Whether or not you are pregnant or breastfeeding
- Biaxin may cause elevated liver enzymes and liver inflammation.
- Biaxin may cause a serious heart rhythm disorder called QT prolongation, especially in patients with abnormal electrolytes, low heart rate, or in patients taking Class IA (quinidine, procainamide) or Class III (dofetilide, amiodarone, sotalol) antiarrhythmic medications, or in patients taking other medications that can prolong the QT interval.
- Baixin may cause an intestinal infection called Clostridium difficile (C. diff).
- Biaxin may worsen or cause symptoms of myasthenia gravis, an autoimmune disorder that leads to muscle weakness.
- Pregnant women should not take Biaxin unless there is no other appropriate therapeutic option. Biaxin may cause harm to an unborn fetus.
Side Effects
Common Biaxin side effects include diarrhea, nausea, altered taste, indigestion, stomach pain or discomfort, headache, and rash; however, you should contact your doctor right away if you develop side effects that bother you or won't resolve.
Reference:
- Biaxin (clarithromycin). North Chicago, IL: Abbott Laboratories; n.d.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 1380
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