What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Bezalip SR (Bezafibrate)
Also Known as Bezlip Mono, Calberzol XL
Prescription Required
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Product Details
Description
Bezalip SR is a medication that can be prescribed to treat cholesterol disorders. It is indicated for treating abnormally high lipids (hyperlipidemia) and abnormally high triglycerides (hypertriglyceridemia).
Bezalip SR works by increasing the number of certain enzymes in the body that help to break down the types of cholesterol called VLDL and triglycerides. It also prevents the body from making more triglyceride molecules.
Bezalip SR medication has not been approved for use in the United States by the Food and Drug Administration (FDA).
Fact Table
Formula
C19H20ClNO4
License
US FDA
Bioavailability
100%
Legal status
US: Rx-only
Chemical Name
Bezafibrate
Elimination half-life
2 hours
Dosage (Strength)
400mg
Pregnancy
Limited data
Brands
Bezalip SR
Protein binding
95%
PubChem CID
39042
MedlinePlus
a682711
ChEBI
47612
ATC code
C10AB02
DrugBank
DB01393
KEGG
D01366
Routes of administration
Oral
Directions
The dosage of Bezalip SR is usually 400 mg by mouth once daily.
This medication may be taken with or without food.
Ingredients
The active ingredient in this product is bezafibrate. It belongs to a class of medications called fibrates.
Interactions
Bezalip SR has significant drug-drug interactions. Tell your doctor and pharmacy about all medications you are taking, including:
- Acipimox
- Atorvastatin
- Bile Acid Sequestrants
- Ciprofibrate
- Colchicine
- Cyclosporine
- Ezetimibe
- Glimepiride
- Glipizide
- Glyburide
- Lovastatin
- Monoamine Oxidase Inhibitors (MAOIs)
- Raltegravir
- Rosuvastatin
- Simvastatin
- Ursodiol
- Warfarin
Cautions
This medication can cause mild increases in some liver enzymes. Tell your doctor if you have liver problems before starting this medication.
Cholesterol medications have been associated with muscle pain and wasting (rhabdomyolysis). This condition is rare but serious. It is more common when taking multiple medications for cholesterol.
Use is not recommended for adults over 70 years of age.
Side Effects
Bezalip SR side effects may include:
- Anemia
- Bronchitis
- Constipation
- Diarrhea
- Dizziness
- Dyspepsia
- Eczema
- Epigastric distress
- Erythema
- Gastritis
- Flatulence
- Headache
- Increased kidney enzymes
- Increased liver enzymes
- Insomnia
- Migraine
- Nausea
- Pain
- Pharyngitis
- Pruritus
- Urticaria
If your side effects are severe or long-lasting, talk to your doctor. You may need a different medication.
References
Bezalip [package insert]. Mississauga, ON: Allergan; 2019.
Frequently Asked Questions about Bezalip SR (Bezafibrate)
What is Bezalip SR (Bezafibrate)?
Bezalip SR is a medication that contains the active ingredient Bezafibrate. It belongs to a class of drugs known as fibrates and is used to treat high levels of fats (lipids) in the blood, including high cholesterol and triglycerides.
How does Bezalip SR work?
Bezalip SR works by reducing the levels of triglycerides and low-density lipoprotein cholesterol (LDL-C) in the blood while increasing high-density lipoprotein cholesterol (HDL-C). It helps improve the balance of lipids in the bloodstream.
Who should take Bezalip SR (Bezafibrate)?
Bezalip SR is typically prescribed to individuals with elevated cholesterol or triglyceride levels, especially when dietary and lifestyle changes alone are insufficient to control these lipid levels.
What are the common side effects of Bezalip SR?
Common side effects of Bezalip SR may include gastrointestinal symptoms like nausea, abdominal discomfort, and diarrhea. Muscle pain or weakness can also occur. Be sure to report any unusual or severe side effects to your doctor.
How is Bezalip SR taken?
Bezalip SR is usually taken orally in the form of extended-release tablets. The dosage and frequency will depend on your specific condition and your doctor's instructions. It's important to take it as prescribed.
Can I take Bezalip SR with other medications?
Inform your healthcare provider about all the medications, supplements, and herbal products you are taking to avoid potential drug interactions. Some medications may interact with Bezalip SR, so your doctor can make appropriate adjustments.
Is Bezalip SR safe during pregnancy or breastfeeding?
If you are pregnant, planning to become pregnant, or breastfeeding, discuss the use of Bezalip SR with your healthcare provider. They will assess the risks and benefits to determine if it is safe for you.
Can I stop taking Bezalip SR once my lipid levels improve?
Do not stop taking Bezalip SR without consulting your healthcare provider, even if your lipid levels improve. Stopping the medication prematurely may result in a recurrence of high cholesterol or triglycerides.
Is Bezalip SR available over-the-counter (OTC)?
Bezalip SR is typically available by prescription only. It is not available as an over-the-counter medication.
How long can I take Bezalip SR (Bezafibrate)?
The duration of Bezalip SR treatment will depend on your individual lipid profile and your doctor's recommendations. Some individuals may require long-term use to maintain healthy lipid levels.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 12293
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