What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Betagan (Levobunolol) eyedrops
Prescription Required
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Product Details
Description
Betagan is a prescription medication used to treat increased eye pressure in conditions such as glaucoma and ocular hypertension. Elevated intraocular pressure can lead to optic nerve damage and vision loss if left untreated.
Levobunolol is a non-selective beta-blocker that reduces the production of aqueous humor (the fluid inside the eye), thereby lowering intraocular pressure. Betagan helps prevent further optic nerve damage and preserves vision by managing eye pressure.
Fact Table
Formula
C17H25NO3
License
US FDA
Bioavailability
~78% (ocular absorption)
Legal status
Prescription only (Rx)
Chemical Name
(2R)-5-[3-(tert-Butylamino)-2-hydroxypropoxy]-3,4-dihydro-1H-naphthalen-2-one
Elimination half-life
~6 hours (systemic)
Dosage (Strength)
0.5% solution
Pregnancy
Consult a doctor
Brands
Betagan
Protein binding
~50%
PubChem CID
39011
MedlinePlus
a605025
ChEBI
CHEBI:63612
ATC code
S01ED05
DrugBank
DB01210
KEGG
D08154
Routes of administration
Ophthalmic (eye drops)
Directions
Instill one drop of Betagan in the affected eye(s) once or twice daily, as your healthcare provider prescribes. Use the drops at the same time each day to maintain consistent eye pressure control.
Do not touch the tip of the bottle to the eye because this can contaminate the product and lead to bacterial or viral infection.
Ingredients
The active ingredient is levobunolol.
Interactions
The most common drug-drug interactions may include:
- Albuterol
- Ceritinib
- Clonidine
- Crizotinib
- Darunavir
- Diltiazem
- Dronedarone
- Epinephrine
- Fenoldopam
- Fingolimod
- Formoterol
- Indacaterol
- Iohexol
- Lacosamide
- Levalbuterol
- Olodaterol
- Oxymetazoline
- Ponesimod
- Rivastigmine
- Salmeterol
- Terbutaline
- Verapamil
- Vilanterol
Cautions
Do not use Betagan if you are allergic to levobunolol or any other ingredients in the solution.
Betagan can cause drowsiness or blurred vision. Avoid driving or operating machinery until you know how this medication affects you.
Tell your doctor if you have a history of asthma, heart problems, diabetes, or thyroid problems before starting this drug.
Do not instill Levobunolol drops at the same time as other eye drop medications. If you use other eye drops, space the administration by at least 15 minutes.
If you wear contact lenses, wait 15 minutes after using this drug to place them.
Side Effects
Common side effects of this drug may include:
- Blepharoconjunctivitis
- Bradyarrhythmia
- Bronchospasm
- Burning sensation in eye
- Choroidal detachment
- Congestive heart failure
- Heart block
- Stevens-Johnson syndrome
References
Betagan [package insert]. Irvine, CA: Allergan; 2017.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 1374
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