Description
Bactroban is a nasal ointment used for the treatment of nasal colonization of methicillin-resistant Staphylococcus aureus (MRSA). It can be used by adults, pediatric patients, and healthcare workers to prevent the spread of MRSA institutional outbreaks in high-risk locations.
Bactroban works by binding to bacterial isoleucyl-transfer RNA (tRNA) synthetase. This protein is important for the replication of bacterial cells. At concentrations in this formulation, Bactroban is bactericidal (kills bacterial cells).
Bactroban is no longer available in the United States due to supply shortages.
Directions
Apply Bactroban nasal ointment into each nostril twice daily for 5-10 days or as directed by your healthcare provider.
Apply Bactroban nasal ointment to a clean dry area.
Do not get the ointment into the eyes or other mucus membranes.
Ingredients
The active ingredient in Bactroban is mupirocin.
Interactions
There are no known significant interactions.
Do not mix Bactroban Nasal Ointment with other topical medications prior to administration. Mixing it with other medications may cause it to not work as well.
Cautions
If Bactroban causes irritation at the application site, stop using it and tell your doctor right away.
Do not take Bactroban for longer or shorter than prescribed.
Use caution if you have a history of kidney problems.
Tell your doctor if you have an allergy to benzyl alcohol or polyethylene glycol before using this drug.
Side Effects
The most common side effects of this medication can include:
- Abdominal Pain
- Aphthous Stomatitis
- Blepharitis
- Cellulitis
- Clostridioides Difficile-Associated Diarrhea
- Contact Dermatitis
- Cough
- Dermatitis
- Diarrhea
- Dizziness
- Dysgeusia
- Epistaxis
- Erythema
- Headache
- Hypersensitivity Reaction
- Increased Wound Secretion
- Local Pain
- Localized Burning
- Localized Edema
- Localized Tenderness
- Nausea
- Otalgia
- Pharyngitis
- Pruritus
- Respiratory Congestion
- Rhinitis
- Skin Rash
- Stinging Sensation
- Urticaria
- Wound Infection
- Xeroderma
- Xerostomia
References
Bactroban Nasal Ointment [package insert]. Research Triangle Park, NC: GlaxoSmithKline; 2017.
About Dr. Conor Sheehy (Page Author)
Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 11664