What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Axid (Nizatidine)
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Product Details
Description
Axid is an oral medication that your healthcare provider may prescribe to treat painful stomach conditions. It is commonly prescribed for gastrointestinal reflux disease (GERD), benign gastric ulcer, duodenal ulcer, and Helicobacter pylori infection.
These conditions commonly cause symptoms like eructation (burping), heartburn, nausea, abdominal discomfort, and bitter taste in the mouth.
Axid is a histamine receptor antagonist and works on histamine receptors on the surface of stomach cells. By blocking histamine receptors, Axid reduced the amount of stomach acid secreted by stomach cells.
Fact Table
Formula
C12H21N5O2S2
License
US FDA
Bioavailability
More than 70%
Legal status
US: OTC / Rx-only
Chemical Name
Nizatidine
Elimination half-life
1–2 hours
Dosage (Strength)
150mg, 300mg
Pregnancy
Not Recommended
Brands
Axid, Tazac
Protein binding
35%
PubChem CID
3033637
MedlinePlus
a694030
ChEBI
7601
ATC code
A02BA04
DrugBank
DB00585
KEGG
D00440
Routes of administration
By mouth
Directions
For the treatment of duodenal ulcer or gastric ulcer, the starting dosage is 150 mg by mouth twice daily. It can be increased to 300 mg twice daily. A full course may last up to 8 weeks. Some doctors may have you continue Axid 150 mg once daily for long-term maintenance.
For the treatment of GERD, the standard dosage is 150 mg twice daily for 12 weeks.
To treat Helicobacter pylori infection, the standard dosage of Axid 150 mg twice daily for 10-14 days in combination with other medications.
Ingredients
Axid generic is called nizatidine, which is the active ingredient in the medication.
Interactions
Common drug-drug interactions with Axid medications can include:
- Atazanavir
- Cefpodoxime
- Cefuroxime
- Dasatinib
- Erlotinib
- Fosamprenavir
- Gefitinib
- Indinavir
- Ketoconazole
- Multivitamins/Minerals
- Nilotinib
- Octreotide
- Posaconazole
- Rilpivirine
- Risedronate
- Saquinavir
- Varenicline
- Velpatasvir
Tell your doctor and pharmacist about all medications you are taking before starting Axid.
Cautions
Long-term usage may lead to vitamin B12 deficiency. This effect is more likely to occur in females under 30 years of age.
Use with caution if you have a history of kidney problems.
Side Effects
Common adverse reactions may include:
- Abdominal pain
- Anorexia
- Anxiety
- Constipation
- Diarrhea
- Dizziness
- Fever
- Flatulence
- Headache
- Heartburn
- Insomnia
- Irritability
- Nasal congestion
- Nasopharyngitis
- Nausea
- Nervousness
- Pruritus
- Vomiting
- Xerostomia
References
- Axid [package insert]. Liberty Corner, NJ: Reliant; 2005.
Frequently Asked Questions about Axid (Nizatidine)
What is Axid (Nizatidine)?
Axid is a brand name for the medication Nizatidine. It belongs to a class of drugs known as H2 blockers and is used to reduce stomach acid production.
What conditions does Axid treat?
Axid is primarily used to treat conditions where excessive stomach acid production causes problems, such as heartburn, GERD (gastroesophageal reflux disease), and stomach or duodenal ulcers.
How does Axid work?
Axid works by blocking the action of histamine on stomach cells, which reduces the production of stomach acid. This helps alleviate symptoms associated with excessive stomach acid.
Who should take Axid?
Axid is typically prescribed to individuals who have been diagnosed with conditions like heartburn, GERD, or ulcers. It is important to follow your healthcare provider's recommendations regarding its use.
What are the common side effects of Axid?
Common side effects of Axid may include headache, dizziness, constipation, diarrhea, and abdominal pain. If you experience any unusual or severe side effects, consult your doctor.
How is Axid taken?
Axid is usually taken orally as a tablet or liquid. The dosage and frequency will depend on your specific condition, so it's essential to follow your doctor's instructions carefully.
Can I take Axid (Nizatidine) with other medications?
It's essential to inform your healthcare provider about all the medications, supplements, and herbal products you are taking to avoid potential drug interactions. Some drugs may interact with Axid.
Can I stop taking Axid once my symptoms improve?
Do not stop taking Axid without consulting your healthcare provider, even if your symptoms improve. Stopping the medication prematurely may lead to a recurrence of symptoms.
Is Axid available over-the-counter (OTC)?
In some countries, lower-dose forms of Nizatidine may be available over-the-counter for short-term use. However, higher doses typically require a prescription.
How long can I take Axid?
The duration of Axid treatment will depend on your specific condition and your healthcare provider's recommendations. Some individuals may need short-term treatment, while others may require longer-term use.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 1362
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