Description
Auvi-Q is a prescription product that contains the active ingredient epinephrine. It is used for emergencies like anaphylactic allergic reactions. People with possibly fatal allergies should carry epinephrine on them if there is a chance they will be in contact with the allergen.
Epinephrine works by shutting down the symptoms of severe allergies like trouble breathing, swollen throat, and rash.
Fact Table |
Formula |
C9H13NO3 |
License |
US FDA |
Bioavailability |
very low |
Legal status |
Rx-Only |
Chemical Name |
Epinephrine |
Elimination half-life |
2 minutes |
Dosage (Strength) |
0.3mg, 0.15mg |
Pregnancy |
No Known Risks |
Brands |
EpiPen, Adrenaclick |
Protein binding |
15–20% |
PubChem CID |
5816 |
MedlinePlus |
a603002 |
ChEBI |
28918 |
ATC code |
A01AD01 |
DrugBank |
DB00668 |
KEGG |
D00095 |
Routes of administration |
IV, IM, endotracheal, IC, nasal, eye drop |
Directions
Auvi-Q is dosed based on weight. Ask your doctor or pharmacist to show you how to use it.
Ingredients
The active ingredient in Auvi-Q is epinephrine.
Interactions
Use caution if you are taking any of the following drugs. However, in a life-threatening emergency, Auvi-Q should be given even at the risk of interactions.
- Blonanserin
- Alpha1-Blockers
- Antidiabetic Agents
- Atomoxetine
- Benperidol
- Benzylpenicilloyl Polylysine
- Beta-Blockers
- Bretylium
- Bromocriptine
- Bromperidol
- Cannabinoid-Containing Products
- Chloroprocaine
- CloZAPine
- Cocaine (Topical)
- COMT Inhibitors
- Doxofylline
- Ergot Derivatives (Vasoconstrictive CYP3A4 Substrates)
- Guanethidine
- Haloperidol
- Hyaluronidase
- Inhalational Anesthetics
- Kratom
- Linezolid
- Lisuride
- Monoamine Oxidase Inhibitors
- Ozanimod
- Pergolide
- Promethazine
- Serotonin/Norepinephrine Reuptake Inhibitors
- Solriamfetol
- Spironolactone
- Sympathomimetics
- Tedizolid
- Tricyclic Antidepressants
- Vasopressin
Cautions
Seek immediate hospital care after using Auvi-Q.
Use as directed. Auvi-Q is only intended for intramuscular injection in the leg.
Auvi-Q may worsen symptoms of heart disease.
Side Effects
Common side effects may include:
- Angina Pectoris
- Anxiety
- Apprehension
- Asthenia
- Cardiac Arrhythmia
- Cardiomyopathy
- Cerebral Hemorrhage
- Cerebrovascular Accident
- Chest Pain
- Diaphoresis
- Disorientation
- Dizziness
- Drowsiness
- Dyspnea
- Exacerbation of Parkinson Disease
- Gangrene of Skin or Other Tissue
- Headache
- Hyperglycemia
- Hypertension
- Hypoglycemia
- Hypokalemia
- Increased Cardiac Work
- Insulin Resistance
- Ischemic Heart Disease
- Lactic Acidosis
- Limb Ischemia
- Localized Blanching
- Memory Impairment
- Myocardial Infarction
- Nausea
- Pallor
- Palpitations
- Panic
- Paresthesia
- Peripheral Vasoconstriction
- Piloerection
- Psychomotor Agitation
- Pulmonary Edema
- Rales
- Renal Insufficiency
- Restlessness
- Supraventricular Tachycardia
- Tachyarrhythmia
- Tachycardia
- Tingling Sensation
- Tissue Necrosis at Injection Site
- Tremor
- Vasoconstriction
- Ventricular Arrhythmia
- Ventricular Ectopy
- Ventricular Fibrillation
- Vomiting
References
- Auvi-Q [package insert]. Richmond, VA: Kaleo, Inc.; 2017.
About Dr. Conor Sheehy (Page Author)
Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 13259