Description
Anusol Plus (Zinc Sulfate and Pramoxine Hydrochloride) is a topical ointment formulated for the treatment of hemorrhoids. Anusol Plus hemorrhoidal ointment treatment can help alleviate discomfort, itchiness, and swelling caused by hemorrhoidal conditions.
Fact Table |
Formula |
C21H30O5 (Hydrocortisone) and ZnSO4 (Zinc Sulfate) |
License |
US DailyMed |
Bioavailability |
NNo data available for topical bioavailability. Systemic absorption is low |
Legal status |
Rx-only |
Chemical Name |
IHydrocortisone / Zinc Sulfate |
Elimination half-life |
No data for topical use. Oral hydrocortisone has a plasma half-life of 1.5-2 hours |
Dosage (Strength) |
0.5% |
Pregnancy |
Category C - Use with caution if benefits outweigh risks |
Brands |
Anusol HC Ointment |
Protein binding |
90% bound to plasma proteins (hydrocortisone) |
PubChem CID |
5754 (Hydrocortisone) and 61012024 (Zinc Sulfate) |
MedlinePlus |
a605030 |
ChEBI |
168410 (Hydrocortisone) and 95769 (Zinc Sulfate) |
ATC code |
D07AA02 - Hydrocortisone, combinations |
DrugBank |
DB00635 (Hydrocortisone) |
KEGG |
D00093 (Hydrocortisone) |
Routes of administration |
Topical/rectal |
Directions
Anusol Plus ointment is applied directly to the affected area. Before applying the medication, clean the affected area with mild soap and water and then rinse the area well or pat dry with a toilet tissue or soft pad. Apply a small amount of the ointment to the affected area up to 5 times daily, especially at night, in the morning, or after each bowel movement. Follow the instructions on the packaging or consult with your healthcare provider for specific directions.
Ingredients
Each tube of Anusol Plus contains zinc sulfate and pramoxine hydrochloride as active ingredients.
Contraindications
Do not use Anusol Plus if you are allergic to zinc sulfate, pramoxine hydrochloride, or any other ingredient in Anusol Plus.
Cautions
- Before using Anusol Plus, inform your doctor or pharmacist:
- If you have any allergies to the ingredients
- If you have any existing health conditions or are taking any other medications
- If you are pregnant or plan to become pregnant
- If you are nursing or plan to nurse your baby
- Wash your hands thoroughly before and after applying the ointment.
- Do not ingest Anusol Plus; it is for external use only.
- Avoid contact with eyes, and if contact occurs, rinse immediately with water.
- Consult your healthcare provider if symptoms persist or worsen after 7 days of treatment.
- Store Anusol Plus at room temperature, away from moisture and heat.
- Keep it out of reach of children and pets.
Side Effects
The common side effects of Anusol Plus include skin irritation, redness, or a burning sensation at the application site. If you experience any side effects that worsen or persist, contact your doctor or pharmacist immediately. In rare cases, allergic reactions may occur. Seek immediate medical attention if you notice any signs of a serious allergic reaction, such as rash, swelling, severe dizziness, or trouble breathing.
References:
Anusol Plus Product Label. Ewing, NJ: Church & Dwight; 2023.
About Dr. Gerardo Sison (Page Author)
Dr. Sison graduated with honors from the University of Florida. He began his career in pharmacy counseling patients in a community setting and later served in hospitals and clinics. He has also worked in medication therapy management services. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 13190