What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Ampicillin (Generic)
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Product Details
Description
Ampicillin is a prescription antibiotic used to treat different types of bacterial infections. It is more commonly used as a step down after intravenous (IV) ampicillin to continue treatment of an ongoing infection.
The oral (capsule) version is indicated to treat:
- Gastrointestinal infections
- Genitourinary infections
- Respiratory tract infections
Ampicillin belongs to the penicillin family of antibacterial agents. It works by preventing bacteria from forming a bacterial cell wall. Without a cell wall, the bacteria's natural protection breaks down, and they stop growing.
Fact Table
Formula
C16H19N3O4S
License
US FDA, EU EMA
Bioavailability
62% ±17%
Legal status
Rx-only
Chemical Name
Ampicillin
Elimination half-life
1 hour
Dosage (Strength)
250mg, 500mg
Pregnancy
No Known Risk
Brands
Generic
Protein binding
15 to 25%
PubChem CID
6249
MedlinePlus
a685002
ChEBI
28971
ATC code
J01CA01
DrugBank
DB00415
KEGG
D00204
Routes of administration
By mouth
Directions
Take ampicillin exactly as directed by your healthcare provider. The dose will vary depending on the type and severity of the infection.
The normal ampicillin dose is three to four times per day.
Ampicillin is available in 250 mg and 500 mg capsules.
Ingredients
Ampicillin is a generic drug, and the active ingredient is ampicillin.
Interactions
Ampicillin has many potential drug-drug interactions. Tell your doctor and pharmacist about everything you are taking before starting this medication. Common interactions include:
- Allopurinol
- Aminoglycosides
- Atenolol
- BCG
- Chloroquine
- Cholera vaccine
- Dichlorphenamide
- Lactobacillus and Estriol
- Lanthanum
- Methotrexate
- Mycophenolate
- Probenecid
- Sodium picosulfate
- Tetracycline
- Typhoid vaccines
- Warfarin
Cautions
A rash is a common side effect of ampicillin and is commonly confused with a hypersensitivity reaction (allergic reaction). Your healthcare provider should carefully evaluate the rash if it develops.
Use caution if you have kidney problems.
Long-term use of ampicillin can cause the bacterial infection C.diff. Tell your doctor if you have prolonged severe diarrhea while using this medication.
Side Effects
The most common Ampicillin side effects may include:
- Agranulocytosis
- Anemia
- Diarrhea
- Dysgeusia
- Enterocolitis
- Eosinophilia
- Erythema multiforme
- Exfoliative dermatitis
- Fever
- Glossalgia
- Glossitis
- Hemolytic anemia
- Immune thrombocytopenia
- Increased liver enzymes
- Interstitial nephritis
- Leukopenia
- Melanoglossia
- Nausea
- Oral candidiasis
- Penicillin-induced brain disease
- Pseudomembranous colitis
- Seizure
- Serum sickness-like reaction
- Skin rash
- Sore mouth
- Stomatitis
- Stridor
- Urticaria
- Vomiting
References
- Ampicillin [package insert]. Princeton, NJ: Sandoz; 2020.
Frequently Asked Questions about Ampicillin (Generic)
What is Ampicillin (Generic)?
Ampicillin (Generic) is an antibiotic medication used to treat various bacterial infections.
How does Ampicillin work?
Ampicillin works by inhibiting the formation of bacterial cell walls, leading to the destruction of the bacteria.
What conditions does Ampicillin treat?
Ampicillin is effective against respiratory, urinary tract, skin, and gastrointestinal tract infections caused by susceptible bacteria.
Is Ampicillin suitable for viral infections?
No, Ampicillin is only effective against bacterial infections and does not work on viral infections like the common cold or flu.
How should I take Ampicillin?
Take Ampicillin as prescribed by your healthcare provider, usually on an empty stomach with a full glass of water.
Are there any side effects of Ampicillin?
Common side effects include diarrhea, nausea, and rash. Contact your doctor if you experience severe side effects.
Can I drink alcohol while taking Ampicillin?
It is advisable to avoid alcohol while on Ampicillin as it may reduce the drug's effectiveness and increase the risk of side effects.
What should I do if I miss a dose of Ampicillin?
Take the missed dose as soon as you remember. However, if it's almost time for the next dose, skip the missed one and continue with the regular schedule.
Can pregnant or breastfeeding women take Ampicillin?
Pregnant or breastfeeding women should consult their healthcare provider before taking Ampicillin to assess potential risks and benefits.
Is it safe to drive or operate machinery while on Ampicillin?
Ampicillin may cause dizziness; therefore, it's important to assess your individual response before engaging in activities that require alertness.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 11953
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