What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Altabax (Retapamulin)
Also Known as Altargo
Prescription Required
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Product Details
Description
Altabax is a prescription ointment that can be used by patients nine months and older. It is available with a prescription from a health provider. Altabax is a topical medication applied to the skin for the treatment of impetigo due to Staphylococcus aureus. Your doctor may need to test the skin to determine if the infection is due to this type of bacteria.
Impetigo is a bacterial infection that is more common in children and is sometimes referred to as school sores. The primary symptom is red sores around the face and mouth that may rupture and form a yellowish-brown crust.
Altabax is an antibacterial agent that prevents infective bacteria from forming critical proteins that help the bacteria grow.
Fact Table
Formula
C30H47NO4S
License
US FDA, EU EMA
Bioavailability
Low
Legal status
Rx-only
Chemical Name
Retapamulin
Elimination half-life
Undetermined
Dosage (Strength)
1%
Pregnancy
No Known Risk
Brands
Altabax, Altargo
Protein binding
94%
PubChem CID
6918462
MedlinePlus
a607049
ChEBI
166679
ATC code
D06AX13
DrugBank
DB01256
KEGG
D05720
Routes of administration
Topical
Directions
The usual directions are to apply a thin layer to the affected area twice daily for five days.
The area may be covered with sterile gauze or a bandage if needed.
Altabax should be applied to a clean and dry area of the skin and give the medication enough time to absorb into the skin without washing it off. Wash hands after application.
Ingredients
The active ingredient in Altabax ointment is 10 mg of retapamulin per 1 gram of ointment.
Interactions
Common drug-drug interactions with Altabax may include:
- Atazanavir
- Ceritinib
- Clarithromycin
- Cobicistat
- Darunavir
- Idelalisib
- Indinavir
- Itraconazole
- Ketoconazole
- Lonafarnib
- Lopinavir
- Mifepristone
- Nefazodone
- Nelfinavir
- Ombitasvir-paritaprevir-ritonavir
- Posaconazole
- Ritonavir
- Saquinavir
- Telithromycin
- Tucatinib
- Voriconazole
Cautions
Altabax is only for use on the skin and should not be used in the eyes, nose, mouth, or genitals.
Stop taking Altabax if you experience severe irritation.
Side Effects
Common adverse reactions include:
- Angioedema
- Application site burning
- Application site irritation
- Application site pain
- Application site pruritus
- Contact dermatitis
- Diarrhea
- Eczema
- Epistaxis
- Erythema
- Headache
- Hypersensitivity reaction
- Increased creatinine phosphokinase
- Nasopharyngitis
- Nausea
References
Altabax [package insert]. Research Triangle Park, NC: GlaxoSmithKline; 2012.
Frequently Asked Questions about Altabax (Retapamulin)
What is Altabax (Retapamulin)?
Altabax (Retapamulin) is a topical antibiotic medication used to treat bacterial skin infections.
How does Altabax work?
Altabax works by inhibiting bacterial protein synthesis, effectively treating and eliminating skin infections caused by susceptible bacteria.
What conditions does Altabax treat?
Altabax is primarily used for the treatment of impetigo, a contagious skin infection commonly caused by bacteria.
How is Altabax applied?
Apply a thin layer of Altabax to the affected skin area twice daily for a prescribed duration, as directed by your healthcare provider.
Is Altabax suitable for children?
Altabax is generally safe for children aged 9 months and older, but it's essential to consult with a healthcare professional for proper guidance.
Are there any potential side effects of Altabax?
Common side effects may include itching or redness at the application site. If you experience severe reactions, contact your healthcare provider.
Can I use Altabax if I'm pregnant or breastfeeding?
Inform your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding before using Altabax, as caution may be necessary.
How long does it take for Altabax to show results?
Improvement is usually seen within a few days of starting treatment. However, complete the full course as prescribed by your doctor.
Can I use Altabax for conditions other than impetigo?
Altabax is specifically indicated for impetigo and should not be used to treat other skin conditions without consulting your healthcare provider.
What should I do if I miss a dose of Altabax?
If you miss a dose, apply it as soon as you remember. However, if it's almost time for the next dose, skip the missed one and continue with the regular schedule. Do not double up on doses to make up for a missed application.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 12816
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