Alprolix (Factor IX Recombinant)
What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
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Prescription Required
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Product Details
Description
Alprolix (Coagulation Factor IX (Recombinant), Fc Fusion Protein) is a prescription treatment for bleeding episodes, management of bleeding during surgery, and prevention to help decrease the number of bleeding episodes in adults and children who have hemophilia B.
Alprolix is administered intravenously (in a vein).
Fact Table
Formula
C1985H3067N547O590S28
License
US FDA, EMA
Bioavailability
50-80%
Legal status
Prescription only
Chemical Name
Factor IX (recombinant)
Elimination half-life
82 hours
Dosage (Strength)
500 IU, 1000 IU, 2000 IU, 3000 IU per vial
Pregnancy
Consult a doctor
Brands
Alprolix
Protein binding
N/A
PubChem CID
16132911
MedlinePlus
a614030
ChEBI
63637
ATC code
B02BD04
DrugBank
DB00030
KEGG
D02379
Routes of administration
Intravenous
Directions
Your healthcare provider will decide on a treatment plan, including Alprolix dosing, that’s appropriate for you. Alprolix will be administered via an intravenous infusion by your healthcare provider. If you have any questions, talk to your healthcare provider.
Ingredients
The active ingredient in Alprolix is Coagulation Factor IX (Recombinant), Fc Fusion Protein.
Contraindications
Patients with an allergy to any of the ingredients in Alprolix should not receive it.
Cautions
- Before you begin receiving Alprolix, talk to your healthcare provider about:
- All the prescription and over-the-counter medications you take
- Your allergies
- Your current health problems and past medical history
- Your pregnancy or breastfeeding status
- Hypersensitivity reactions, including anaphylaxis, can occur.
- Antibodies may form that can stop Alprolix from adequately working.
- Blood clotting problems can occur.
- Kidney problems can occur.
Side Effects
Headache, abnormal sensation in the mouth, and pain in your side with blood in the urine are common side effects of Alprolix. However, other side effects may also occur. Immediately inform your healthcare provider of side effects that bother you or won’t go away.
Ask your healthcare provider about Alprolix.
References:
Alprolix. Waltham, MA: Bioverativ Therapeutics Inc.; 2023.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 14447
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