Description
Allerject, also known as Epinephrine, is a life-saving medication classified as a sympathomimetic drug. It works quickly to counteract the severe symptoms of anaphylactic reactions by stimulating alpha and beta adrenergic receptors. Its main role is to relax the airway muscles for easier breathing and to narrow blood vessels, raising blood pressure that often drops during an allergic emergency. Allerject is available as a pre-measured, voice-guided autoinjector, providing a precise dose for individuals at risk of or experiencing anaphylaxis, typically triggered by allergens such as foods, insect stings, or medications.
Directions
Allerject is an Epinephrine auto-injector designed for the emergency treatment of severe allergic reactions known as anaphylaxis. It is available in two dosages: 0.15 mg for individuals who weigh between 15 to 30 kilograms (33 to 66 pounds) and 0.3 mg for those weighing over 30 kilograms (66 pounds). When an allergic emergency occurs, the user should firmly press the device against their outer thigh until it clicks, indicating that the injection has started, and hold it in place for 3 seconds. The injection can be administered through clothing if necessary.
After using Allerject, it's important to seek immediate medical attention. Even if the device's voice instructions are not functioning, the Allerject auto-injector should still be used as directed. Patients should carry Allerject with them at all times in case of accidental exposure to their allergen. They should also ensure they are trained on the correct use of the auto-injector and be aware that repeat injections may be required for severe or persistent allergic symptoms.
Ingredients
The active ingredient in Allerject is Epinephrine.
Contraindications
There are no contraindications listed on the Allerject label. However, individuals with a known hypersensitivity to Epinephrine or other ingredients in the formulation should avoid using the medication.
Cautions
- Prior to initiating treatment with Allerject, make sure to disclose the following to your healthcare provider:
- Any existing health conditions
- Known allergies
- A complete list of medications you are currently using
- Your status regarding pregnancy or breastfeeding
- Always carry Allerject if you've previously experienced severe allergies, and wear a medical ID.
- After using Allerject, seek immediate medical help, as it's not a replacement for professional care.
- Only use antihistamines or asthma medications after administering Allerject, not as first-line treatments.
- Refill your Allerject prescription immediately after an anaphylactic episode.
- Administer Allerject only into the front of your thigh. Avoid injecting into other areas such as the buttocks, hands, or feet to prevent serious complications.
- Hold the leg steady during injection, especially for children, to avoid movement and potential injury.
- Monitor the injection site for signs of infection like redness or swelling, and seek medical attention if these symptoms appear.
- Avoid injecting Allerject into the buttocks due to the risk of serious infection.
- If you have heart problems, high blood pressure, diabetes, or asthma, discuss the use of Allerject with your doctor since it requires extra caution.
- Be aware of potential allergic reactions to sulfites in Allerject, but remember that the immediate need for epinephrine during a severe allergic reaction is critical.
Side Effects
People who use Allerject may experience anxiety, tremors, dizziness, sweating, rapid heartbeat, palpitations, nausea, and headaches shortly after injection. These symptoms are typically mild to moderate and resolve quickly with rest.
More severe reactions can occur, particularly in individuals with existing health conditions like heart disease or hyperthyroidism. Serious side effects include significant increases in blood pressure, ventricular arrhythmias, and more rarely, stress-induced cardiomyopathy, primarily affecting younger women. There's also a risk of severe infections at the injection site, such as necrotizing fasciitis, if the injection is administered improperly or into areas with insufficient blood flow, like the buttocks. While these reactions are rare, they underscore the need for immediate medical attention if complications arise post-injection.
References:
Allerject (Epinephrine Injection) Product Monograph. Kirkland, Quebec: Valeo Pharma, Inc.; 2022.
About Dr. Gerardo Sison (Page Author)
Dr. Sison graduated with honors from the University of Florida. He began his career in pharmacy counseling patients in a community setting and later served in hospitals and clinics. He has also worked in medication therapy management services. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 13798