What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Aczone Gel (Dapsone)
Prescription Required
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Product Details
Description
Aczone 7.5% is a prescription gel product used to treat Acne vulgaris in patients 12 years of age and older. Aczone is a topical medication applied to the skin. It should not be ingested or used internally.
Acne vulgaris is a chronic condition of the skin where pores, where hair follicles reside, become plugged with dead skin cells or oil. Acne vulgaris is the same condition common amongst teenagers and adults.
Symptoms of acne vulgaris may include inflamed blackheads, pus-filled pimples, and painful red bumps on the face.
Fact Table
Formula
C12H12N2O2S
License
US FDA
Bioavailability
70 to 80%
Legal status
Rx-only
Chemical Name
Dapsone
Elimination half-life
20 to 30 hours
Dosage (Strength)
5%
Pregnancy
Consult Doctor
Brands
Aczone
Protein binding
70 to 90%
PubChem CID
2955
MedlinePlus
a682128
ChEBI
4325
ATC code
D10AX05
DrugBank
DB00250
KEGG
D00592
Routes of administration
By mouth
Directions
Apply a small amount to the affected area of the face once daily as directed by your physician. Aczone may be used on other parts of the body as directed by a healthcare professional.
Do not mix Aczone with other topical medications.
Follow the Aczone gel directions provided by your physician.
Ingredients
The active ingredient in Aczone is dapsone.
It is not known how dapsone works to treat acne vulgaris.
If your acne symptoms do not improve within 12 weeks after starting Aczone, talk to your doctor. You may need to try a different medication.
Interactions
Common drug-drug interactions with Aczone may include:
- Anesthetics
- Benzoyl peroxide
- Methemoglobinemia
- Nitric oxide
- Prilocaine
- Sodium nitrite
- Trimethoprim
Tell your doctor about any new medications you start while taking Aczone or other prescription medications.
Cautions
Tell your doctor if you have a history of Glucose-6-phosphate dehydrogenase (G6PD) deficiency before you start using Aczone. Aczone may worsen a condition called hemolysis.
Tell your doctor if you have a history of methemoglobinemia. Aczone has been known to rarely cause this condition.
Side Effects
Some of the common Aczone gel side effects of Aczone may include:
- Application site rash
- Erythematous rash
- Facial edema
- Lip edema
- Periorbital swelling
- Sinusitis
- Skin rash
References
Aczone [package insert]. Irvine, CA: Allergan; 2016.
Frequently Asked Questions about Aczone Gel (Dapsone)
What is Aczone Gel (Dapsone)?
Aczone Gel, also known by its generic name Dapsone, is a topical medication used to treat acne. It belongs to a class of drugs called sulfone antibiotics.
How does Aczone Gel work for acne?
Aczone Gel works by reducing inflammation and targeting the bacteria associated with acne. It helps to clear existing acne lesions and prevent new ones from forming.
Who can use Aczone Gel for acne treatment?
Aczone Gel is typically prescribed for individuals aged 12 years and older who have acne vulgaris.
Is Aczone Gel suitable for all types of acne?
Aczone Gel is primarily used for the treatment of acne vulgaris. Your healthcare provider will determine if it's an appropriate treatment option based on your specific type and severity of acne.
Are there any common side effects of Aczone Gel?
Common side effects of Aczone Gel may include dryness, redness, itching, or peeling of the skin at the application site. If you experience severe or unusual side effects, consult your healthcare provider.
How should I apply Aczone Gel?
Aczone Gel is typically applied to the affected areas of the skin once daily. Follow the instructions provided by your healthcare provider, and make sure your skin is clean and dry before application.
Can I use Aczone Gel during pregnancy or while breastfeeding?
It's important to discuss the use of Aczone Gel during pregnancy or while breastfeeding with your healthcare provider. They can provide guidance on potential risks and benefits.
How long does it take to see results with Aczone Gel?
The time it takes to see noticeable improvements in your acne can vary. Some individuals may see results within a few weeks, while others may require more time. Consistent use is important.
Can Aczone Gel be used in combination with other acne treatments?
Your healthcare provider may recommend using Aczone Gel in combination with other acne treatments, such as topical or oral medications, to enhance its effectiveness.
Is regular follow-up with a healthcare provider necessary while using Aczone Gel?
Yes, regular follow-up appointments with your healthcare provider are important while using Aczone Gel. They can monitor your progress, assess the treatment's effectiveness, and make any necessary adjustments.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 12154
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