What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Acuvail (Ketorolac Tromethamine) Ophthalmic Solution
Prescription Required
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Product Details
Description
Acuvail (ketorolac tromethamine ophthalmic solution) 0.45% is a prescription eye drop used to treat pain and inflammation of the eyes after cataract surgery.
Acuvail comes in single-dose vials packaged in three foil pouches; each pouch contains 10 vials.
Fact Table
Formula
C15H13NO3•C4H11NO3
License
US FDA
Bioavailability
Topical (ophthalmic): Limited systemic absorption
Legal status
Prescription only
Chemical Name
(±)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid, compound with 2-amino-2-(hydroxymethyl)propane-1,3-diol (1:1)
Elimination half-life
4 to 6 hours (systemic, oral)
Dosage (Strength)
0.45% solution
Pregnancy
Consult a doctor
Brands
Acuvail, Acular, Toradol
Protein binding
~99% (systemic, oral)
PubChem CID
3823
MedlinePlus
a614002
ChEBI
CHEBI:6122
ATC code
S01BC05
DrugBank
DB00465
KEGG
D00134
Routes of administration
Ophthalmic
Directions
Acuvail should be used as directed by your doctor. The recommended dose is to apply one drop to the affected eye two times a day beginning one day before cataract surgery and continuing through the first two weeks after surgery.
Do not use Acuvail while wearing contact lenses.
You may refer to the medication leaflet that comes with your prescription for further instructions for use.
Store between 15oC to 30oC (59oF to 86oF) in the pouch, with pouch ends folded closed, away from light exposure. Use the solution from one single-dose vial immediately after opening and discard the remaining contents of the vial.
Talk to your doctor or pharmacist about any questions or concerns you have.
Ingredients
The active ingredient in Acuvail is ketorolac tromethamine, a nonsteroidal anti-inflammatory drug.
Contraindications
Patients with an allergy to any of the ingredients in Acuvail eye drops should not use it.
Cautions
- Before you begin using Acuvail, inform your doctor of:
- All the prescription and over-the-counter medications you use, including other eye medications
- Your allergies
- Your current health problems and past medical history
- Your pregnancy or breastfeeding status
- Acuvail contains the following warnings and precautions:
- Delayed healing
- Hypersensitivity or cross-sensitivity
- Increased bleeding time because of interference with thrombocyte aggregation
- Keratitis or other corneal effects
Side Effects
Increased intraocular pressure, conjunctival hemorrhage, and blurry vision are common Acuvail side effects; however, other side effects may also occur.
Immediately tell your doctor if you experience side effects that bother you or persist.
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Reference
Acuvail. North Chicago, IL: AbbVie Inc.; 2024.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 11614
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