What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Acular LS (ketorolac)
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Product Details
Description
ACULAR LS (ketorolac tromethamine) is an ophthalmic medication used after different types of eye surgery.
ACULAR LS belongs to the medication class non-steroidal anti-inflammatory (NSAID). NSAIDs like ACULAR LS reduce pain, inflammation, swelling, and redness where they are applied. Ketorolac works by blocking the enzymes cyclooxygenase 1 and cyclooxygenase 2. Blocking these enzymes prevents cells of the immune system from activating.ACULAR LS is used after the following surgeries: cataract extraction, corneal refractive surgery, and cataract surgery. It can also be used to treat ocular itching that occurs with seasonal allergies.
Directions
Instill one drop to the affected eye(s) four times daily or as directed by your doctor. Sometimes ACULAR LS is applied only twice daily.
Do not touch the tip of the dropper directly onto the eye. Contact with the eye can cause contamination by viruses or bacteria, which can lead to eye infections.
Remove contact lenses before applying and wait at least 10 minutes before putting them back in.
Ingredients
The active ingredient in ACULAR LS is ketorolac tromethamine 0.4%.
The name for ACULAR LS generic is also ketorolac tromethamine.
Interactions
Since eye medications are not absorbed into the bloodstream, they do not have drug interactions with most other medications.
However, when using other eye drops, separate their administration by at least five minutes.
Fact Table
Formula
C15H13NO3
License
AU, EU EMA, US FDA
Bioavailability
80-100% (oral) 100% IV/IM
Legal status
RX Only
Chemical Name
Ketorolac
Elimination half-life
3.5 h to 9.2 h, Young adults;4.7 h to 8.6 h, Elderly (mean age 72)
Dosage (Strength)
LS 0.4% (5mL)
Pregnancy
Consult a doctor
Brands
Acular, Acuvail, Omidria, Readysharp Anesthetics Plus Ketorolac, Sprix, Toradol, Toronova Suik
Protein binding
99%
PubChem CID
3826
MedlinePlus
a693001
ChEBI
6129
ATC code
M01AB15, S01BC05
DrugBank
DB00465
KEGG
D08104
Routes of administration
By mouth, under the tongue, intramuscular, intravenous, eye drops, nasal spray
Cautions
Long-term use can lead to adverse effects on the cornea, including erosion, perforation, ulceration, and keratitis. Do not use this medication for longer than instructed by your doctor.
Tell your doctor if you have a known allergy to NSAIDs.
Side Effects
The most common side effects that can happen while using ACULAR LS include
- Allergic reactions
- Conjunctival hyperemia
- Corneal edema
- Corneal infiltrates
- Headache
- Irritation
- Ocular edema
- Ocular inflammation
- Ocular pain
- Transient stinging and burning
References
Acular LS [package insert].Palo Alto, CA: Allergan; 2003.
Frequently Asked Questions about Acular LS (ketorolac)
What is Acular LS (ketorolac)?
Acular LS (ketorolac) is a nonsteroidal anti-inflammatory drug (NSAID) used in eye drop form to reduce pain and inflammation in the eyes.
What is Acular LS used for?
Acular LS is commonly prescribed to reduce pain and inflammation following eye surgery. It may also be used for other conditions as determined by a healthcare professional.
How should I use Acular LS?
Always use Acular LS as directed by your doctor. Typically, it is applied as drops to the affected eye(s). Ensure your hands are clean before applying, and avoid touching the dropper tip to prevent contamination.
Are there any side effects of Acular LS?
As with any medication, Acular LS can have side effects. Common side effects include eye irritation, burning, or stinging. If you experience severe side effects or allergic reactions, such as swelling, redness, or difficulty breathing, contact your doctor immediately.
Can I use Acular LS with other eye medications?
If you are using other eye medications, inform your doctor. It's essential to wait at least 5 minutes between applying different eye drops to prevent interactions.
What should I avoid while using Acular LS?
Avoid wearing contact lenses while using Acular LS unless your doctor advises otherwise. Also, avoid driving or performing activities that require clear vision until you know how the medication affects you.
Can I use Acular LS if I'm pregnant or breastfeeding?
If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before using Acular LS.
How should I store Acular LS?
Store Acular LS in a cool, dry place away from direct sunlight. Keep it out of reach of children and pets.
What should I do if I miss a dose?
If you miss a dose, apply it as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular schedule.
Can I overdose on Acular LS?
If you suspect an overdose or if the medication is ingested, seek medical attention immediately.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 9283
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