What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Actigall (Ursodiol)
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Product Details
Description
ACTIGALL (ursodiol) is a prescription medication that can treat and prevent gallstones.
The gallbladder is an organ by the liver that helps with digestions. It produces bile, which is a digestive fluid that contains several different enzymes and cholesterol.
ACTIGALL works in the liver to reduce the amount of cholesterol that is produced. By reducing the production of cholesterol, bile is less likely to form into stones.
Left untreated, gallstones can cause biliary obstruction, leading to pain and digestive problems.
Fact Table
Formula
C24H40O4
License
US FDA, EU EMA
Bioavailability
-
Legal status
Rx-Only
Chemical Name
Ursodiol
Elimination half-life
Not Available
Dosage (Strength)
300mg
Pregnancy
Consult Doctor
Brands
Actigall, Urso
Protein binding
70%
PubChem CID
31401
MedlinePlus
a699047
ChEBI
9907
ATC code
A05AA02
DrugBank
DB01586
KEGG
D00734
Routes of administration
By mouth
Directions
If taking ACTIGALL for gallstone dissolution, the normal dose is 8-10 mg/kg/day in 2 to 3 divided doses.
For gallstone prevention, the normal dose is 300 mg by mouth twice daily.
Ingredients
The active ingredient in ACTIGALL is ursodiol.
Ursodiol is the name for ACTIGALL generic.
Cautions
Tell your doctor if you have a history of chronic liver disease. People will chronic liver disease will need regular tests to make sure ACTIGALL is not impacting the liver.
Continue taking ACTIGALL as long as directed by your doctor. It may take several months for a gallstone to dissolve.
Interactions
Actigall can interact with the following drugs:
- Aluminum hydroxide
- Bile acid sequestrants
- Estrogen products (oral contraceptives)
- Fibric acid derivatives
- Nitrendipine
- Sincalide
Side Effects
ACTIGALL has many possible adverse reactions. The most common ones include:
- Alopecia
- Arthritis
- Back pain
- Bronchitis
- Cholecystitis
- Constipation
- Cough
- Diarrhea
- Dizziness
- Dyspepsia
- Headache
- Hyperglycemia
- Hypersensitivity reaction
- Increased kidney enzymes
- Leukopenia
- Musculoskeletal pain
- Nausea
- Peptic ulcer
- Pharyngitis
- Skin rash
- Thrombocytopenia
- Upper respiratory tract infection
- Urinary tract infection
- Viral infection
- Vomiting
Speak with your doctor or pharmacist for a full list of side effects that are most likely to impact you.
Search Canada Pharmacy for the best ACTIGALL cost, and buy ACTIGALL online with a valid prescription from your doctor.
References
Actigall [package insert]. Madison, NJ: Allergan; 2018.
Frequently Asked Questions about Actigall (Ursodiol)
What is Actigall (Ursodiol)?
Actigall is a prescription medication that contains the active ingredient Ursodiol. It belongs to a class of drugs known as bile acid modifiers and is primarily used to dissolve gallstones in individuals who cannot undergo surgery or have a specific type of gallstone.
How Does Actigall Work?
Actigall works by decreasing the production of cholesterol in the liver and by reducing the amount of cholesterol absorbed by the intestines. This helps in dissolving cholesterol gallstones over time.
Can Actigall Be Used to Prevent Gallstones?
Actigall is not typically used to prevent gallstones but is primarily prescribed to dissolve existing cholesterol gallstones in individuals with specific medical conditions.
Is Actigall (Ursodiol) Available Over-the-Counter (OTC)?
No, Actigall is not available over-the-counter. It is a prescription medication, and you must consult a healthcare provider to obtain it.
Are There Any Common Side Effects Associated with Actigall?
Common side effects of Actigall may include diarrhea, upset stomach, and abdominal pain. It's important to discuss potential side effects with your healthcare provider.
Can I Take Other Medications Alongside Actigall?
It is important to inform your healthcare provider about all the medications, supplements, or herbal remedies you are taking, as some may interact with Actigall and affect its effectiveness.
How Long Does It Take for Actigall to Dissolve Gallstones?
The time it takes for Actigall to dissolve gallstones can vary widely among individuals. It may take several months of treatment, and in some cases, it may not be successful.
Is It Safe to Use Actigall During Pregnancy?
Actigall should be used during pregnancy only if the potential benefits outweigh the risks. If you are pregnant or planning to become pregnant, consult your healthcare provider for guidance.
Can Actigall Be Taken While Breastfeeding?
It is important to discuss the use of Actigall while breastfeeding with your healthcare provider. They will assess the potential benefits and risks and provide guidance on its use during this period.
How Often Will I Need to Monitor My Gallstones While Taking Actigall?
Your healthcare provider will determine how often you should have imaging tests, such as ultrasound, to monitor the progress of gallstone dissolution while taking Actigall.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 9498
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