What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Aciphex (Rabeprazole)
Also Known as Pariet,Parit
Prescription Required
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Product Details
Description
Aciphex Generic Uses and Side Effects
Chemical Name: RABEPRAZOLE (ra-BE-pray-zole)
Aciphex is used to treat symptoms of gastroesophageal reflux disease (GERD) and other conditions involving excessive stomach acid such as Zollinger-Ellison syndrome. It is also used to promote healing of erosive esophagitis (damage to your esophagus caused by stomach acid).
Aciphex may also be given with an antibiotic to prevent gastric ulcer caused by infection with helicobacter pylori (H. pylori).
ACIPHEX is not intended for immediate relief of heartburn symptoms.
Fact Table
Formula
C18H21N3O3S
License
FDA approved
Bioavailability
Not completely absorbed (about 52% after oral administration)
Legal status
Prescription only (US: Rx-only)
Chemical Name
Rabeprazole
Elimination half-life
Approximately 1-2 hours
Dosage (Strength)
Tablets: 20 mg, 10 mg
Pregnancy advice
Category B (No evidence of risk in studies)
Brands
Aciphex, Pariet, others
Protein binding
96.3%
PubChem CID
5029
MedlinePlus
a699060
ChEBI
CHEBI:8768
ATC code
A02BC04
DrugBank
DB01129
KEGG
D08463
Routes of administration
Oral
Directions
Use ACIPHEX exactly as directed by your healthcare professional. Do not change your doses or dosing schedule without consulting your healthcare professional. Generally, ACIPHEX is prescribed for 4 to 8 weeks only. Your doctor may recommend a second course of treatment if you need additional healing time.
ACIPHEX may be taken with or without food. It is recommended to take this medication with a full glass (8 ounces) of water. Do not crush, break, or chew - swallow the tablet whole. Breaking or tampering with the tablet may alter the effects of the medication. Take this medication for the full prescribed length of time.
Cautions
Not all medications work effectively for every patient, therefore it is important to consult your doctor about any health conditions, especially liver disease, if you have low magnesium levels in your blood, pregnant or planning on becoming pregnant and/or if you are breastfeeding.
Do not use ACIPHEX if you are allergic to rabeprazole or similar medications such as Prevacid, Nexium, Prilosec, Zegerid or Protonix.
Taking this medication may increase your risk of bone fracture in the hip, wrist, or spine. This effect mostly appeared in patients who took the medication over a long period of time or at high doses, (age 50+). It is unclear whether ACIPHEX is the actual cause of an increased risk of fracture however patients should inform their healthcare professional if they have osteoporosis or osteopenia.
Side Effects
All medication has side effects which may vary from serious to mild. Patients should remember that their healthcare professional has prescribed ACIPHEX because they feel the benefits of taking this medication outweigh the risk of side effects.
Contact your healthcare professional immediately if you have serious side effects, including:
- Dizziness or confusion
- Fast or uneven heart rate
- Jerking muscle movements
- Feelings of jitteriness
- Muscle cramps, weakness or limp feeling
- Cough or choking feeling
- Seizure or convulsions
- Severe headache
- Upset stomach or diarrhea
- Insomnia
- Nervousness
- Rash or itchy skin
This is not a complete list of possible side effects. If you notice other effects, contact your healthcare professional immediately.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 2127
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