What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Accupril (Quinapril)
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Product Details
Description
Accupril, classified as an angiotensin-converting enzyme (ACE) inhibitor, is a prescription medication used to treat high blood pressure. It is also used with other medications to treat heart failure.
Accupril is supplied in 5 mg, 10 mg, 20 mg, and 40 mg oral tablets.
The Accupril generic is quinapril.
Directions
Take Accupril exactly as your doctor has prescribed. Tell your doctor or pharmacist about any questions or concerns you may have.
When used alone for treating high blood pressure, Accupril is generally dosed at 10 mg or 20 mg by mouth once daily; however, the dose may be adjusted based on response and tolerance to the medication. A diuretic (water pill) may be added to the treatment regimen if blood pressure is not adequately controlled with Accupril alone.
When used to treat heart failure, Accupril is generally started at a dose of 5 mg by mouth twice daily. The dose may be adjusted based on response and tolerance to the medication.
Patients with kidney problems may require a lower Accupril dose.
Ingredients
Quinapril is the active ingredient in Accupril.
Contraindications
Do not take Accupril if you are allergic to any of its ingredients or if you have ever had angioedema (swelling) caused by an ACE-inhibitor.
Do not take Accupril with a neprilysin inhibitor such as sacubitril. You should avoid taking Accupril for at least 36 hours of switching to or from a neprilysin inhibitor such as sacubitril/valsartan.
If you have diabetes, you should not take Accupril with aliskiren.
Cautions
Accupril has an FDA Boxed Warning that it can cause harm or death to a developing fetus. Accupril should be discontinued right away when pregnancy is detected.
- Before you start taking Accupril, it is important that you tell your doctor about:
- All the prescription and nonprescription medications you take
- Your allergies
- Your past medical history and current health problems
- If you are pregnant or breastfeeding
- Accupril can cause anaphylactoid and related reactions. These reactions can also occur during desensitization with hymenoptera venom and during high-flux membrane exposure associated with dialysis.
- Accupril can cause angioedema of the face, arms, legs, lips, tongue, glottis, and larynx. If any of these effects occur, seek emergency care right away.
- Intestinal angioedema can occur with the use of Accupril, which can cause stomach pain with or without nausea or vomiting.
- Although rare, Accupril can cause liver failure.
- Accupril can cause low blood pressure.
- Accupril can cause abnormal white blood cell counts, especially in patients who experienced these abnormal counts with previous treatment with captopril, another ACE inhibitor. Patients with kidney problems, collagen vascular disease, or lupus may be at greater risk.
- Accupril can impair kidney function.
- Accupril can cause high potassium levels in the blood.
- Accupril can cause a dry cough.
- Caution should be used if you are undergoing surgery or anesthesia.
Side Effects
Accupril side effects include headache, dizziness, fatigue, coughing, nausea, vomiting, and stomach pain; however, these are not the only side effects that may occur. Contact your doctor right away if you have side effects that worry you or will not resolve.
Reference:
Accupril. New York, NY: Parke-Davis; 2022.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 1308
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