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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Vemlidy (Tenofovir Alafenamide)

Brand

Vemlidy (Tenofovir Alafenamide)

Prescription Required

Strength
Qty
25mg

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  • Product Details

    Description

    Vemlidy (tenofovir alafenamide) is a prescription medication used to treat hepatitis B virus in adults and children who are at least 12 years of age and have compensated liver disease.

    Vemlidy comes in 25 mg tablets for oral administration.

    Fact Table

    Formula

    C21H29O5N6P

    License

    US FDA, EMA, Health Canada

    Bioavailability

    Approximately 35% (higher intracellular delivery than TDF)

    Legal status

    Prescription only (Rx)

    Chemical Name

    Tenofovir alafenamide fumarate

    Elimination half-life

    150–180 hours (intracellular); ~0.5 hours (plasma)

    Dosage (Strength)

    25 mg oral tablet, once daily

    Pregnancy

    Use only if clearly needed; no known teratogenicity but consult a doctor

    Brands

    Vemlidy

    Protein binding

    80%

    PubChem CID

    71661245

    MedlinePlus

    a617042

    ChEBI

    133725

    ATC code

    J05AF13

    DrugBank

    DB09299

    KEGG

    D10566

    Routes of administration

    Oral

    Directions

    Take Vemlidy exactly as prescribed by your doctor. Carefully read the information for safe use that accompanies your prescription. Do not hesitate to reach out to your doctor or pharmacist about any questions or concerns you may have.

    The recommended dose is to take one tablet by mouth once daily. Take with food.

    Store Vemlidy below 30°C (86°F) and away from children’s reach.

    Ingredients

    Tenofovir alafenamide is the active ingredient in each Vemlidy tablet. Inactive ingredients include croscarmellose sodium, lactose monohydrate, magnesium stearate, microcrystalline cellulose, iron oxide yellow, polyethylene glycol, polyvinyl alcohol, talc, and titanium dioxide.

    Contraindications

    There are no contraindications, or reasons why a person cannot take Vemlidy, per the most recent Prescribing Information. However, patients should consult with their doctor about a treatment regimen that's best for them.

    Cautions

    • Vemlidy contains the following FDA Boxed Warning:
      • Discontinuing hepatitis B treatment may worsen hepatitis B. Patients who stop taking Vemlidy should receive close monitoring of their liver function. Resumption of hepatitis B treatment may be required.
    • Before you start treatment with Vemlidy, talk to your doctor about:
      • All the prescription and over-the-counter medications you take
      • Your allergies
      • Your current health problems and past medical history
      • Your pregnancy or breastfeeding status
    • Vemlidy by itself should not be used to treat HIV-1 infection.
    • New or worsening kidney problems may occur.
    • Lactic acidosis and severe liver enlargement may occur.

    Side Effects

    The most common Vemlidy side effect is headache. However, other side effects may also occur. Contact your doctor right away if you have side effects that bother you or won’t go away.

    Looking for a competitive Vemlidy price? Here, you can buy Vemlidy.

    Reference

    1. Vemlidy. Foster City, CA: Gilead Sciences, Inc.; 2022.


    Dr Savannah Muncy
    About Dr. Savannah Muncy (Page Author)


    Dr. Muncy (PharmD) studied science and education as an undergraduate before attending the Appalachian College of Pharmacy where she completed her PharmD in three years. She is currently using her pharmacy and healthcare expertise to write medical content for clients all around the world. She is focused on delivering the most current, accurate, and engaging information to healthcare professionals and patients. Read More....


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 14383

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