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What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Tri-Luma(Fluocinolone/Hydroquinone/Tretinoin)
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Product Details
Description
Tri-Luma (fluocinolone acetonide, hydroquinone, and tretinoin) cream, 0.01%/4%/0.05% is a topical medication. Tri-Luma Cream uses include:
- The treatment of brown patches on the face called melasma
Fact Table
Formula
C24H30F2O6 (Fluocinolone), C6H6O2 (Hydroquinone), C20H28O2 (Tretinoin)
License
US FDA
Bioavailability
Minimal systemic absorption (topical)
Legal status
Rx-only
Chemical Name
Fluocinolone acetonide / Hydroquinone / Tretinoin
Elimination half-life
Fluocinolone: ~1.3–1.7 hours; Tretinoin: 0.5–2 hours; Hydroquinone: ~20–40 minutes (topical)
Dosage (Strength)
Fluocinolone 0.01%, Hydroquinone 4%, Tretinoin 0.05% (per gram of cream)
Pregnancy
Contraindicated (Category C)
Brands
Tri-Luma
Protein binding
Tretinoin: 95%; Fluocinolone: Moderate; Hydroquinone: Low
PubChem CID
Fluocinolone: 443858; Hydroquinone: 785; Tretinoin: 444795
MedlinePlus
a699042
ChEBI
Fluocinolone: 31618; Hydroquinone: 17594; Tretinoin: 35623
ATC code
D11AX30
DrugBank
Fluocinolone: DB00188; Hydroquinone: DB09526; Tretinoin: DB00755
KEGG
Fluocinolone: D00599; Hydroquinone: D07855; Tretinoin: D00094
Routes of administration
Topical
Directions
Use Tri-Luma Cream as directed by your doctor. If you have any questions or concerns regarding your prescription, tell your doctor or pharmacist.
The recommended dose is to apply a thin layer of Tri-Luma Cream to the affected area(s) one time a day, at least 30 minutes before bedtime. Wash your hands after using.
Avoid sun exposure, and protect your skin during the day by wearing sunscreen of at least SPF 30 and protective clothing.
Ingredients
The active ingredients in Tri-Luma Cream include fluocinolone acetonide (a corticosteroid), hydroquinone (a melanin synthesis inhibitor), and tretinoin (a retinoid).
Inactive ingredients include butylated hydroxytoluene, cetyl alcohol, citric acid anhydrous, glycerin, glyceryl stearate, magnesium aluminum silicate, methyl gluceth-10, methylparaben, PEG-100 stearate, propylparaben, purified water, sodium metabisulfite, stearic acid, and stearyl alcohol.
Contraindications
Do not use Tri-Luma Cream if you are allergic to any of its ingredients.
Cautions
- Before you start using Tri-Luma Cream, inform your doctor of:
- All the medications you use, including other topical lotions, creams, and ointments
- Your allergies
- Your current health conditions and past medical history
- Your pregnancy or breastfeeding status
- Sodium metabisulfite is present in Tri-Luma Cream, which can cause allergic reactions, including anaphylactic symptoms and serious asthmatic episodes, in patients who are susceptible. Seek emergency care right away if you have trouble breathing, a rash, swelling of your face, lips, or tongue, or any other symptoms of an allergic reaction.
- Tri-Luma Cream contains hydroquinone, which may cause blue-black darkening of the skin. Immediately contact your doctor and avoid using Tri-Luma Cream if this occurs.
- Tri-Luma Cream contains fluocinolone acetonide, which may cause reversible hypothalamic-pituitary-adrenal axis suppression if absorbed systemically. Cushing’s syndrome, high blood glucose, and glucose in the urine may occur.
- Tri-Luma Cream can cause skin irritation, reddening, peeling, burning, dryness, and itching at the application site. Tell your doctor right away if you experience any of these reactions. Patients are recommended to avoid using soaps, cleansers, and cosmetics that are medicated, abrasive, drying, or highly concentrated with alcohol and astringents.
Side Effects
Skin redness, burning, peeling, dryness, and itching are common side effects of Tri-Luma Cream. Other side effects can also occur. Call your doctor right away if you have bothersome or persistent side effects.
Looking for a competitive Tri-Luma Cream price? Buy Tri-Luma Cream right here!
Reference:
- Tri-Luma Cream. Sanford, FL: Hill Dermaceuticals, Inc.; 2014.
Popular Questions
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IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 9393
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