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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
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Synthroid (Levothyroxine) is a medication used to treat hypothyroidism. Hypothyroidism occurs when there is too little thyroid hormone in the body, which can cause a variety of symptoms that impact mood, weight, and body temperature.
The body may have too little thyroid for several reasons, including problems with the thyroid gland itself, problems with the pituitary gland -- which send functional signals to the thyroid gland, differences in genetics (congenital), or acquisition with age.
Synthroid is a synthetic version of the thyroid hormone T4. The generic name is levothyroxine. Synthroid replaces T4 and is converted to active thyroid hormone, T3, in the body.
Synthroid dosages can range from 12.5 to 200 micrograms daily. Some people may require doses above this range.
Synthroid should be taken on an empty stomach, at least 30 minutes before a meal. Synthroid can be taken with water. Take Synthroid in the same manner each day, since food can timing can change how much is absorbed and impact the treatment.
The active ingredient in Synthroid is levothyroxine sodium.
| Fact Table |
|
| Formula |
C15H11I4NO4 |
| License |
EU EMA |
| Bioavailability |
40-80% |
| Legal status |
RX Only |
| Chemical Name |
Levothyroxine |
| Elimination half-life |
7 days in hyperthyroidism 3–4 days, in hypothyroidism 9–10 days |
| Dosage (Strength) |
0.025mg, 0.050mg, 0.075mg, 0.88mg, 0.100mg, 0.112mg, 0.125mg, 0.137mg, 0.150mg, 0.175mg, 0.200mg, 0.300mg (90 tablets) |
| Pregnancy |
Consult a doctor |
| Brands |
Synthroid, Levoxyl, Unithroid, Levothroid |
| Protein binding |
- |
| PubChem CID |
5819 |
| MedlinePlus |
a682461 |
| ChEBI |
18332 |
| ATC code |
H03AA01 |
| DrugBank |
DB00451 |
| KEGG |
D08125 |
| Routes of administration |
By mouth |
Use Synthroid with caution in older adults with underlying cardiovascular disease.
Synthroid requires regular lab monitoring to be effective. Following recommendations from your doctor regarding dose changes and lab monitoring.
Synthroid and other replacement thyroid hormone medications may impact blood glucose control in diabetic patients.
Excess thyroid hormone can decrease bone mineral density, so the lowest effective dose should be used.
If you experience adverse reactions while taking Synthroid, it may be a sign that the dose is too high or too low. Speak with your doctor about any side effects. Common side effects of Synthroid medication include:
What is Synthroid used for?
Synthroid is a thyroid medicine that replaces a hormone normally produced by your thyroid gland. It helps regulate the body’s energy and metabolism. It is primarily used to treat hypothyroidism (low thyroid hormone) when the thyroid does not produce enough of this hormone on its own.
What should I avoid when taking Synthroid?
Avoid taking Synthroid with certain medications, including weight-loss drugs or appetite suppressants. Also, be cautious if you have specific medical conditions such as thyrotoxicosis or symptoms of a heart attack.
What is considered a high dose of Synthroid?
The appropriate dose varies based on individual needs. However, doses exceeding 200 micrograms per day are generally considered high.
How to take Synthroid?
Take Synthroid once a day, consistently at the same time before breakfast. It works best when taken on an empty stomach, with only water.
When to take Synthroid?
Take Synthroid 30 to 60 minutes before breakfast. Remember to wait before eating or drinking anything other than water.
Does Synthroid cause weight gain?
No, Synthroid is not associated with weight gain. In fact, it helps regulate metabolism and energy levels.
How long after taking Synthroid can I drink coffee?
Wait at least 30 minutes to 1 hour after taking Synthroid before consuming coffee or any other beverages or food.
How long does it take for Synthroid to work?
Improvement in symptoms may occur within a few weeks, but it may take several months to achieve optimal results.
Is levothyroxine the same as Synthroid?
Yes, levothyroxine is the generic name for Synthroid. Both contain the same active ingredient and serve the same purpose.
What medications should not be taken with Synthroid?
Be cautious with medications like weight-loss drugs, appetite suppressants, and those that interact with thyroid function. Always consult your doctor.
Prescription Required
