Prescription Required
April 9, 2025 by Lola L. (New York, United States)
“Good. But hoping to be able to fax script”
Medically Reviewed
Please be aware that all information shared here at Canada Pharmacy has been medically reviewed and fact-checked for accuracy. These verifications are made by board-certified medical professionals who have the authority required to state that information related to medical conditions, symptoms, procedures and tests, and standard treatment protocols is valid and truthful. This is based on current guidelines and consensuses shared amongst medical professionals, and in representation of the latest research.
What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Contrave (Bupropion/Naltrexone)
Also Known as Mysimba
We don't have this generic product yet!
Sign up to get exclusive coupon discounts and be the first to be notified when we have this product available.
-
Related Products & Conditions
-
Product Details
Description
Contrave is used with diet and exercise to help manage weight in adults who are:
- Obese or
- Overweight and have a weight-related comorbidity such as diabetes, high blood pressure, or high cholesterol
Contrave is a combination of two medications: naltrexone, an opioid antagonist, and bupropion, an antidepressant. Contrave is available in an extended-release oral tablet containing 8 mg of naltrexone hydrochloride (HCl) and 90 mg of bupropion HCl.
Directions
Take Contrave exactly as your doctor has prescribed. Your dose may be increased every week for four weeks, up to a maximum of 2 tablets by mouth twice daily.
If you have any questions or concerns about your prescription, talk to your doctor or pharmacist.
Ingredients
Each extended-release tablet contains 8 mg of naltrexone hydrochloride (HCl) and 90 mg of bupropion HCl. The inactive ingredients include microcrystalline cellulose, hydroxypropyl cellulose, lactose anhydrous, L-cysteine hydrochloride, crospovidone, magnesium stearate, hypromellose, edetate disodium, lactose monohydrate, colloidal silicon dioxide, Opadry II Blue, and FD and C Blue #2 aluminum lake.
Contraindications
Do not take Contrave medication if you:
- Have uncontrolled high blood pressure
- Have seizure disorders
- Have anorexia nervosa or bulimia
- Are undergoing abrupt discontinuation of alcohol, benzodiazepines, barbiturates, and antiepileptic medications
- Are taking other medications that contain bupropion
- Are taking opioids chronically
- Are taking monoamine oxidase inhibitors (MAOIs)
- Have an allergy to naltrexone, bupropion, or any of the other ingredients in Contrave
Fact Table
Formula
C9H13NO3
License
EU EMA, US FDA
Bioavailability
Unknown
Legal status
RX Only
Chemical Name
Naltrexone/Bupropion
Elimination half-life
5 hours
Dosage (Strength)
8mg or 90mg (112 tablets)
Pregnancy
Consult a doctor
Brands
Contrave
Protein binding
Naltrexone 21%, Bupropion 84%
PubChem CID
11556075
MedlinePlus
a619020
ChEBI
Unknown
ATC code
A08AA62
DrugBank
DB00704
KEGG
D10751
Routes of administration
By mouth
Cautions
- Contrave has a FDA Boxed Warning regarding an increased risk of suicidal thoughts or behavior. Patients who are taking Contrave should be monitored for suicidal thoughts or behaviors.
- Before you start treatment with Contrave, it's important that you tell your doctor about:
- All the medications you take
- Your allergies
- Your health history and current health problems
- Your pregnancy or breastfeeding status
- While quitting smoking, neuropsychiatric adverse events such as mood changes, psychosis, hallucinations, paranoia, agitation, and anxiety can occur in patients taking Contrave. If any of these effects occur, patients should contact their doctor right away.
- The risk of seizures may be reduced with adherence to the dosing schedule and avoiding a high-fat meal when taking Contrave.
- Heart rate and blood pressure can increase with the use of Contrave.
- Liver damage can occur with the use of Contrave.
- Glaucoma can occur with the use of Contrave.
- Low blood sugar may occur with the use of antidiabetic medications and weight loss that can occur with Contrave.
Side Effects
The most common Contrave side effects include nausea, constipation, headache, vomiting, dizziness, sleep problems, dry mouth, and diarrhea. However, these are not all the side effects that can occur. Call your doctor right away if you develop bothersome or persistent side effects.
Reference:
Contrave. Brentwood, TN: Currax™ Pharmaceuticals, LLC; 2021.
Popular Questions
Common side effects of Contrave include nausea, constipation, headache, vomiting, dizziness, sleep problems, dry mouth, and diarrhea. Being aware of potential side effects helps patients and healthcare providers weigh the benefits and risks of treatment.
The rate of weight loss on Contrave can vary among individuals, but clinical studies suggest that people may lose an average of 5-10% of their starting body weight over the course of a year when combined with a reduced-calorie diet and increased physical activity. Some people may notice weight loss within the first few weeks, but it's important to follow a healthcare provider's guidance and have realistic expectations about gradual weight loss. Individual results can vary based on factors like adherence to lifestyle changes, metabolic rate, and overall health.
Contrave is used with diet and exercise to help manage weight in adults who are obese or overweight and have a weight-related comorbidity such as diabetes, high blood pressure, or high cholesterol. This provides value by offering a medically-supported option for individuals struggling with weight management, particularly those with additional health concerns.
The inactive ingredients include microcrystalline cellulose, hydroxypropyl cellulose, lactose anhydrous, L-cysteine hydrochloride, crospovidone, magnesium stearate, hypromellose, edetate disodium, lactose monohydrate, colloidal silicon dioxide, Opadry II Blue, and FD and C Blue #2 aluminum lake. These components aid in the delivery and absorption of the active ingredients, enhancing the overall effectiveness of the medication.
The elimination half-life of Contrave is approximately 5 hours. This information is valuable for understanding how long the drug stays active in the body, which can impact dosing schedules and potential interactions with other medications.
Patients taking Contrave should be monitored for suicidal thoughts or behaviors due to the FDA Boxed Warning. Monitoring ensures early detection and management of potential adverse effects, enhancing patient safety.
Patients should contact their doctor right away if they experience mood changes, psychosis, hallucinations, paranoia, agitation, or anxiety. Prompt response to these effects ensures timely intervention, reducing potential harm.
To reduce the risk of seizures, patients should adhere to the dosing schedule and avoid a high-fat meal when taking Contrave. This guidance helps minimize adverse effects and maximize the safety of the medication.
The active ingredients in Contrave are naltrexone, an opioid antagonist, and bupropion, an antidepressant. These components work together to aid in weight management, providing value by targeting different pathways related to appetite and mood.
View allContrave should be taken exactly as prescribed by your doctor, with the dosage potentially increasing every week for four weeks, up to a maximum of 2 tablets by mouth twice daily. This ensures the medication is tailored to individual needs, maximizing its effectiveness and safety.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13241
-
Product Reviews
We're currently collecting product reviews for this item. In the meantime, here are some reviews from our past customers sharing their overall shopping experience.4.8Out of 5.0
Overall Rating95%of customers that buy
from this merchant give
them a 4 or 5-Star rating.April 9, 2025 by Philip S. (New Jersey, United States)“Easy peasy”April 9, 2025 by Colette G. (Florida, United States)“Very simple to do.”April 9, 2025 by Michael S. (Pennsylvania, United States)“very easy”April 9, 2025 by Jill F. (OR, United States)“Thank you for making it easy”April 8, 2025 by betty D. (California, United States)“GOOD”April 8, 2025 by Molly S. (WA, United States)“Once I figured out how to navigate it's gone really well. It did seem to take a while for Rx to ship. And now fur my second order Rx Mankato is out of stock. I've been chatting with live agent to get answers but they don't have any update. I also asked if the vial versus the one woukd be in stock and they said it may take a day or two to find out. This is an area that could improve but the agents seem to be trying. Thanks fir asking!”April 8, 2025 by Wayne M. (ME, United States)“How do you send payment the pay for it shipment”April 8, 2025 by Zenaida O. (Florida, United States)“AnaMarie did helped us a lot. and ordering was very easy.”April 8, 2025 by Patrick B. (Minnesota, United States)“So far so good”
